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Page 1
Animal models for COVID-19.
Muñoz-Fontela C, Dowling WE, Funnell SGP, Gsell PS, Riveros-Balta AX, Albrecht RA, Andersen H, Baric RS, Carroll MW, Cavaleri M, Qin C, Crozier I, Dallmeier K, de Waal L, de Wit E, Delang L, Dohm E, Duprex WP, Falzarano D, Finch CL, Frieman MB, Graham BS, Gralinski LE, Guilfoyle K, Haagmans BL, Hamilton GA, Hartman AL, Herfst S, Kaptein SJF, Klimstra WB, Knezevic I, Krause PR, Kuhn JH, Le Grand R, Lewis MG, Liu WC, Maisonnasse P, McElroy AK, Munster V, Oreshkova N, Rasmussen AL, Rocha-Pereira J, Rockx B, Rodríguez E, Rogers TF, Salguero FJ, Schotsaert M, Stittelaar KJ, Thibaut HJ, Tseng CT, Vergara-Alert J, Beer M, Brasel T, Chan JFW, García-Sastre A, Neyts J, Perlman S, Reed DS, Richt JA, Roy CJ, Segalés J, Vasan SS, Henao-Restrepo AM, Barouch DH. Muñoz-Fontela C, et al. Among authors: brasel t. Nature. 2020 Oct;586(7830):509-515. doi: 10.1038/s41586-020-2787-6. Epub 2020 Sep 23. Nature. 2020. PMID: 32967005 Free PMC article. Review.
An effective CTL peptide vaccine for Ebola Zaire Based on Survivors' CD8+ targeting of a particular nucleocapsid protein epitope with potential implications for COVID-19 vaccine design.
Herst CV, Burkholz S, Sidney J, Sette A, Harris PE, Massey S, Brasel T, Cunha-Neto E, Rosa DS, Chao WCH, Carback R, Hodge T, Wang L, Ciotlos S, Lloyd P, Rubsamen R. Herst CV, et al. Among authors: brasel t. Vaccine. 2020 Jun 9;38(28):4464-4475. doi: 10.1016/j.vaccine.2020.04.034. Epub 2020 Apr 28. Vaccine. 2020. PMID: 32418793 Free PMC article.
The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody.
Chan CEZ, Seah SGK, Chye H, Massey S, Torres M, Lim APC, Wong SKK, Neo JJY, Wong PS, Lim JH, Loh GSL, Wang D, Boyd-Kirkup JD, Guan S, Thakkar D, Teo GH, Purushotorman K, Hutchinson PE, Young BE, Low JG, MacAry PA, Hentze H, Prativadibhayankara VS, Ethirajulu K, Comer JE, Tseng CK, Barrett ADT, Ingram PJ, Brasel T, Hanson BJ. Chan CEZ, et al. Among authors: brasel t. PLoS One. 2021 Jun 23;16(6):e0253487. doi: 10.1371/journal.pone.0253487. eCollection 2021. PLoS One. 2021. PMID: 34161386 Free PMC article.
First vaccine approval under the FDA Animal Rule.
Beasley DWC, Brasel TL, Comer JE. Beasley DWC, et al. NPJ Vaccines. 2016 Aug 25;1:16013. doi: 10.1038/npjvaccines.2016.13. eCollection 2016. NPJ Vaccines. 2016. PMID: 29263855 Free PMC article.
A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates.
Callendret B, Vellinga J, Wunderlich K, Rodriguez A, Steigerwald R, Dirmeier U, Cheminay C, Volkmann A, Brasel T, Carrion R, Giavedoni LD, Patterson JL, Mire CE, Geisbert TW, Hooper JW, Weijtens M, Hartkoorn-Pasma J, Custers J, Grazia Pau M, Schuitemaker H, Zahn R. Callendret B, et al. Among authors: brasel t. PLoS One. 2018 Feb 20;13(2):e0192312. doi: 10.1371/journal.pone.0192312. eCollection 2018. PLoS One. 2018. PMID: 29462200 Free PMC article.
Cell-Type Apoptosis in Lung during SARS-CoV-2 Infection.
Liu Y, Garron TM, Chang Q, Su Z, Zhou C, Qiu Y, Gong EC, Zheng J, Yin YW, Ksiazek T, Brasel T, Jin Y, Boor P, Comer JE, Gong B. Liu Y, et al. Among authors: brasel t. Pathogens. 2021 Apr 23;10(5):509. doi: 10.3390/pathogens10050509. Pathogens. 2021. PMID: 33922476 Free PMC article.
Mucosal Challenge Ferret Models of Ebola Virus Disease.
Brasel T, Comer JE, Massey S, Smith J, Smith J, Hyde M, Kocsis A, Gainey M, Niemuth N, Triplett C, Rudge T Jr. Brasel T, et al. Pathogens. 2021 Mar 4;10(3):292. doi: 10.3390/pathogens10030292. Pathogens. 2021. PMID: 33806375 Free PMC article.
STAT-1 Knockout Mice as a Model for Wild-Type Sudan Virus (SUDV).
Escaffre O, Juelich TL, Neef N, Massey S, Smith J, Brasel T, Smith JK, Kalveram B, Zhang L, Perez D, Ikegami T, Freiberg AN, Comer JE. Escaffre O, et al. Among authors: brasel t. Viruses. 2021 Jul 17;13(7):1388. doi: 10.3390/v13071388. Viruses. 2021. PMID: 34372594 Free PMC article.
Antiviral effect of ranpirnase against Ebola virus.
Hodge T, Draper K, Brasel T, Freiberg A, Squiquera L, Sidransky D, Sulley J, Taxman DJ. Hodge T, et al. Among authors: brasel t. Antiviral Res. 2016 Aug;132:210-8. doi: 10.1016/j.antiviral.2016.06.009. Epub 2016 Jun 25. Antiviral Res. 2016. PMID: 27350309
47 results