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The immune landscape in tuberculosis reveals populations linked to disease and latency.
Esaulova E, Das S, Singh DK, Choreño-Parra JA, Swain A, Arthur L, Rangel-Moreno J, Ahmed M, Singh B, Gupta A, Fernández-López LA, de la Luz Garcia-Hernandez M, Bucsan A, Moodley C, Mehra S, García-Latorre E, Zuniga J, Atkinson J, Kaushal D, Artyomov MN, Khader SA. Esaulova E, et al. Among authors: bucsan a. Cell Host Microbe. 2021 Feb 10;29(2):165-178.e8. doi: 10.1016/j.chom.2020.11.013. Epub 2020 Dec 18. Cell Host Microbe. 2021. PMID: 33340449 Free PMC article.
CD4+ T-cell-independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection.
Foreman TW, Mehra S, LoBato DN, Malek A, Alvarez X, Golden NA, Bucşan AN, Didier PJ, Doyle-Meyers LA, Russell-Lodrigue KE, Roy CJ, Blanchard J, Kuroda MJ, Lackner AA, Chan J, Khader SA, Jacobs WR Jr, Kaushal D. Foreman TW, et al. Among authors: bucsan an. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):E5636-44. doi: 10.1073/pnas.1611987113. Epub 2016 Sep 6. Proc Natl Acad Sci U S A. 2016. PMID: 27601645 Free PMC article.
In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis.
Gautam US, Foreman TW, Bucsan AN, Veatch AV, Alvarez X, Adekambi T, Golden NA, Gentry KM, Doyle-Meyers LA, Russell-Lodrigue KE, Didier PJ, Blanchard JL, Kousoulas KG, Lackner AA, Kalman D, Rengarajan J, Khader SA, Kaushal D, Mehra S. Gautam US, et al. Among authors: bucsan an. Proc Natl Acad Sci U S A. 2018 Jan 2;115(1):E62-E71. doi: 10.1073/pnas.1711373114. Epub 2017 Dec 18. Proc Natl Acad Sci U S A. 2018. PMID: 29255022 Free PMC article.
HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis.
Corleis B, Bucsan AN, Deruaz M, Vrbanac VD, Lisanti-Park AC, Gates SJ, Linder AH, Paer JM, Olson GS, Bowman BA, Schiff AE, Medoff BD, Tager AM, Luster AD, Khader SA, Kaushal D, Kwon DS. Corleis B, et al. Among authors: bucsan an. Cell Rep. 2019 Feb 5;26(6):1409-1418.e5. doi: 10.1016/j.celrep.2019.01.021. Cell Rep. 2019. PMID: 30726727 Free PMC article.
Mechanisms of reactivation of latent tuberculosis infection due to SIV coinfection.
Bucşan AN, Chatterjee A, Singh DK, Foreman TW, Lee TH, Threeton B, Kirkpatrick MG, Ahmed M, Golden N, Alvarez X, Hoxie JA, Mehra S, Rengarajan J, Khader SA, Kaushal D. Bucşan AN, et al. J Clin Invest. 2019 Dec 2;129(12):5254-5260. doi: 10.1172/JCI125810. J Clin Invest. 2019. PMID: 31479428 Free PMC article.
Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques.
Foreman TW, Bucşan AN, Mehra S, Peloquin C, Doyle LA, Russell-Lodrigue K, Gandhi NR, Altman J, Day CL, Ernst JD, Blumberg HM, Rengarajan J, Kaushal D. Foreman TW, et al. Among authors: bucsan an. Am J Respir Crit Care Med. 2020 Feb 15;201(4):469-477. doi: 10.1164/rccm.201903-0646OC. Am J Respir Crit Care Med. 2020. PMID: 31647877 Free PMC article. Retracted.
S100A8/A9 regulates CD11b expression and neutrophil recruitment during chronic tuberculosis.
Scott NR, Swanson RV, Al-Hammadi N, Domingo-Gonzalez R, Rangel-Moreno J, Kriel BA, Bucsan AN, Das S, Ahmed M, Mehra S, Treerat P, Cruz-Lagunas A, Jimenez-Alvarez L, Muñoz-Torrico M, Bobadilla-Lozoya K, Vogl T, Walzl G, du Plessis N, Kaushal D, Scriba TJ, Zúñiga J, Khader SA. Scott NR, et al. Among authors: bucsan an. J Clin Invest. 2020 Jun 1;130(6):3098-3112. doi: 10.1172/JCI130546. J Clin Invest. 2020. PMID: 32134742 Free PMC article.
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