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Multivariate signaling regulation by SHP2 differentially controls proliferation and therapeutic response in glioma cells.
J Cell Sci. 2014 Aug 15;127(Pt 16):3555-67. doi: 10.1242/jcs.150862. Epub 2014 Jun 20.
J Cell Sci. 2014.
PMID: 24951116
Free PMC article.
ERK1/2 blockade prevents epithelial-mesenchymal transition in lung cancer cells and promotes their sensitivity to EGFR inhibition.
Buonato JM, Lazzara MJ.
Buonato JM, et al.
Cancer Res. 2014 Jan 1;74(1):309-19. doi: 10.1158/0008-5472.CAN-12-4721. Epub 2013 Oct 9.
Cancer Res. 2014.
PMID: 24108744
Free PMC article.
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Sprouty2 Drives Drug Resistance and Proliferation in Glioblastoma.
Walsh AM, Kapoor GS, Buonato JM, Mathew LK, Bi Y, Davuluri RV, Martinez-Lage M, Simon MC, O'Rourke DM, Lazzara MJ.
Walsh AM, et al. Among authors: buonato jm.
Mol Cancer Res. 2015 Aug;13(8):1227-37. doi: 10.1158/1541-7786.MCR-14-0183-T. Epub 2015 May 1.
Mol Cancer Res. 2015.
PMID: 25934697
Free PMC article.
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EGFR-activated Src family kinases maintain GAB1-SHP2 complexes distal from EGFR.
Furcht CM, Buonato JM, Lazzara MJ.
Furcht CM, et al. Among authors: buonato jm.
Sci Signal. 2015 May 12;8(376):ra46. doi: 10.1126/scisignal.2005697.
Sci Signal. 2015.
PMID: 25969544
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EGF augments TGFβ-induced epithelial-mesenchymal transition by promoting SHP2 binding to GAB1.
Buonato JM, Lan IS, Lazzara MJ.
Buonato JM, et al.
J Cell Sci. 2015 Nov 1;128(21):3898-909. doi: 10.1242/jcs.169599. Epub 2015 Sep 10.
J Cell Sci. 2015.
PMID: 26359300
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Exocyst Sec10 protects renal tubule cells from injury by EGFR/MAPK activation and effects on endocytosis.
Fogelgren B, Zuo X, Buonato JM, Vasilyev A, Baek JI, Choi SY, Chacon-Heszele MF, Palmyre A, Polgar N, Drummond I, Park KM, Lazzara MJ, Lipschutz JH.
Fogelgren B, et al. Among authors: buonato jm.
Am J Physiol Renal Physiol. 2014 Dec 15;307(12):F1334-41. doi: 10.1152/ajprenal.00032.2014. Epub 2014 Oct 8.
Am J Physiol Renal Physiol. 2014.
PMID: 25298525
Free PMC article.
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Controlling CAR T Cell Activity and Specificity with Synthetic SparX Adapters.
Edwards JP, Swers JS, Buonato JM, Zaritskaya L, Mu CJ, Gupta A, Shachar S, LaFleur DW, Richman LK, Tice DA, Hilbert DM.
Edwards JP, et al. Among authors: buonato jm.
Mol Ther. 2024 Apr 23:S1525-0016(24)00250-8. doi: 10.1016/j.ymthe.2024.04.027. Online ahead of print.
Mol Ther. 2024.
PMID: 38659225
Free article.
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Preclinical Efficacy of BCMA-Directed CAR T Cells Incorporating a Novel D Domain Antigen Recognition Domain.
Buonato JM, Edwards JP, Zaritskaya L, Witter AR, Gupta A, LaFleur DW, Tice DA, Richman LK, Hilbert DM.
Buonato JM, et al.
Mol Cancer Ther. 2022 Jul 5;21(7):1171-1183. doi: 10.1158/1535-7163.MCT-21-0552.
Mol Cancer Ther. 2022.
PMID: 35737298
Free PMC article.
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