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ERK-Mediated Loss of miR-199a-3p and Induction of EGR1 Act as a "Toggle Switch" of GBM Cell Dedifferentiation into NANOG- and OCT4-Positive Cells.
Almairac F, Turchi L, Sakakini N, Debruyne DN, Elkeurti S, Gjernes E, Polo B, Bianchini L, Fontaine D, Paquis P, Chneiweiss H, Junier MP, Verrando P, Burel-Vandenbos F, Virolle T. Almairac F, et al. Cancer Res. 2020 Aug 15;80(16):3236-3250. doi: 10.1158/0008-5472.CAN-19-0855. Epub 2020 May 4. Cancer Res. 2020. PMID: 32366479
EGFR immunolabeling pattern may discriminate low-grade gliomas from gliosis.
Burel-Vandenbos F, Benchetrit M, Miquel C, Fontaine D, Auvergne R, Lebrun-Frenay C, Cardot-Leccia N, Michiels JF, Paquis-Flucklinger V, Virolle T. Burel-Vandenbos F, et al. J Neurooncol. 2011 Apr;102(2):171-8. doi: 10.1007/s11060-010-0308-4. Epub 2010 Jul 24. J Neurooncol. 2011. PMID: 20652725
The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells.
Courtney M, Gjernes E, Druelle N, Ravaud C, Vieira A, Ben-Othman N, Pfeifer A, Avolio F, Leuckx G, Lacas-Gervais S, Burel-Vandenbos F, Ambrosetti D, Hecksher-Sorensen J, Ravassard P, Heimberg H, Mansouri A, Collombat P. Courtney M, et al. PLoS Genet. 2013 Oct;9(10):e1003934. doi: 10.1371/journal.pgen.1003934. Epub 2013 Oct 31. PLoS Genet. 2013. PMID: 24204325 Free PMC article.
A Positive Feed-forward Loop Associating EGR1 and PDGFA Promotes Proliferation and Self-renewal in Glioblastoma Stem Cells.
Sakakini N, Turchi L, Bergon A, Holota H, Rekima S, Lopez F, Paquis P, Almairac F, Fontaine D, Baeza-Kallee N, Van Obberghen-Schilling E, Junier MP, Chneiweiss H, Figarella-Branger D, Burel-Vandenbos F, Imbert J, Virolle T. Sakakini N, et al. J Biol Chem. 2016 May 13;291(20):10684-99. doi: 10.1074/jbc.M116.720698. Epub 2016 Mar 21. J Biol Chem. 2016. PMID: 27002148 Free PMC article.
82 results