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Page 1
Lack of antiviral activity of darunavir against SARS-CoV-2.
De Meyer S, Bojkova D, Cinatl J, Van Damme E, Buyck C, Van Loock M, Woodfall B, Ciesek S. De Meyer S, et al. Among authors: buyck c. Int J Infect Dis. 2020 Aug;97:7-10. doi: 10.1016/j.ijid.2020.05.085. Epub 2020 May 29. Int J Infect Dis. 2020. PMID: 32479865 Free PMC article.
In vitro activity of itraconazole against SARS-CoV-2.
Van Damme E, De Meyer S, Bojkova D, Ciesek S, Cinatl J, De Jonghe S, Jochmans D, Leyssen P, Buyck C, Neyts J, Van Loock M. Van Damme E, et al. Among authors: buyck c. J Med Virol. 2021 Jul;93(7):4454-4460. doi: 10.1002/jmv.26917. J Med Virol. 2021. PMID: 33666253 Free PMC article.
Development and optimization of a high-throughput screening assay for in vitro anti-SARS-CoV-2 activity: Evaluation of 5676 Phase 1 Passed Structures.
Chiu W, Verschueren L, Van den Eynde C, Buyck C, De Meyer S, Jochmans D, Bojkova D, Ciesek S, Cinatl J, De Jonghe S, Leyssen P, Neyts J, Van Loock M, Van Damme E. Chiu W, et al. Among authors: buyck c. J Med Virol. 2022 Jul;94(7):3101-3111. doi: 10.1002/jmv.27683. Epub 2022 Mar 23. J Med Virol. 2022. PMID: 35229317 Free PMC article.
Identification of Z-Tyr-Ala-CHN2, a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2.
Doijen J, Temmerman K, Van den Eynde C, Diels A, Van den Broeck N, Van Gool M, Heo I, Jaensch S, Zwaagstra M, Diosa Toro M, Chiu W, De Jonghe S, Leyssen P, Bojkova D, Ciesek S, Cinatl J, Verschueren L, Buyck C, Van Kuppeveld F, Neyts J, Van Loock M, Van Damme E. Doijen J, et al. Among authors: buyck c. Microorganisms. 2023 Mar 10;11(3):717. doi: 10.3390/microorganisms11030717. Microorganisms. 2023. PMID: 36985290 Free PMC article.
2'-Deoxy-2'-spirocyclopropylcytidine revisited: a new and selective inhibitor of the hepatitis C virus NS5B polymerase.
Jonckers TH, Lin TI, Buyck C, Lachau-Durand S, Vandyck K, Van Hoof S, Vandekerckhove LA, Hu L, Berke JM, Vijgen L, Dillen LL, Cummings MD, de Kock H, Nilsson M, Sund C, Rydegård C, Samuelsson B, Rosenquist A, Fanning G, Van Emelen K, Simmen K, Raboisson P. Jonckers TH, et al. Among authors: buyck c. J Med Chem. 2010 Nov 25;53(22):8150-60. doi: 10.1021/jm101050a. Epub 2010 Oct 29. J Med Chem. 2010. PMID: 21033671
Protocols for the Design of Kinase-focused Compound Libraries.
Jacoby E, Wroblowski B, Buyck C, Neefs JM, Meyer C, Cummings MD, van Vlijmen H. Jacoby E, et al. Among authors: buyck c. Mol Inform. 2018 May;37(5):e1700119. doi: 10.1002/minf.201700119. Epub 2017 Nov 8. Mol Inform. 2018. PMID: 29116686
A small-molecule fusion inhibitor of influenza virus is orally active in mice.
van Dongen MJP, Kadam RU, Juraszek J, Lawson E, Brandenburg B, Schmitz F, Schepens WBG, Stoops B, van Diepen HA, Jongeneelen M, Tang C, Vermond J, van Eijgen-Obregoso Real A, Blokland S, Garg D, Yu W, Goutier W, Lanckacker E, Klap JM, Peeters DCG, Wu J, Buyck C, Jonckers THM, Roymans D, Roevens P, Vogels R, Koudstaal W, Friesen RHE, Raboisson P, Dhanak D, Goudsmit J, Wilson IA. van Dongen MJP, et al. Among authors: buyck c. Science. 2019 Mar 8;363(6431):eaar6221. doi: 10.1126/science.aar6221. Science. 2019. PMID: 30846569 Free PMC article.
Design, Synthesis, and Biological Evaluation of Novel Indoles Targeting the Influenza PB2 Cap Binding Region.
McGowan DC, Balemans W, Embrechts W, Motte M, Keown JR, Buyck C, Corbera J, Funes M, Moreno L, Cooymans L, Tahri A, Eymard J, Stoops B, Strijbos R, Van den Berg J, Fodor E, Grimes JM, Koul A, Jonckers THM, Raboisson P, Guillemont J. McGowan DC, et al. Among authors: buyck c. J Med Chem. 2019 Nov 14;62(21):9680-9690. doi: 10.1021/acs.jmedchem.9b01091. Epub 2019 Oct 30. J Med Chem. 2019. PMID: 31647875 Free PMC article.
Extending kinome coverage by analysis of kinase inhibitor broad profiling data.
Jacoby E, Tresadern G, Bembenek S, Wroblowski B, Buyck C, Neefs JM, Rassokhin D, Poncelet A, Hunt J, van Vlijmen H. Jacoby E, et al. Among authors: buyck c. Drug Discov Today. 2015 Jun;20(6):652-8. doi: 10.1016/j.drudis.2015.01.002. Epub 2015 Jan 14. Drug Discov Today. 2015. PMID: 25596550 Review.
Potent peptidic fusion inhibitors of influenza virus.
Kadam RU, Juraszek J, Brandenburg B, Buyck C, Schepens WBG, Kesteleyn B, Stoops B, Vreeken RJ, Vermond J, Goutier W, Tang C, Vogels R, Friesen RHE, Goudsmit J, van Dongen MJP, Wilson IA. Kadam RU, et al. Among authors: buyck c. Science. 2017 Oct 27;358(6362):496-502. doi: 10.1126/science.aan0516. Epub 2017 Sep 28. Science. 2017. PMID: 28971971 Free PMC article.
18 results