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1844 3
1848 1
1850 1
1851 1
1853 1
1857 1
1858 4
1859 1
1860 1
1861 2
1865 1
1866 1
1867 4
1869 1
1872 2
1873 7
1874 5
1875 6
1876 5
1877 8
1878 6
1879 12
1880 9
1881 9
1882 7
1883 13
1884 7
1885 7
1886 5
1887 6
1888 19
1889 12
1890 12
1891 9
1892 14
1893 6
1894 8
1895 14
1896 5
1897 10
1898 18
1899 11
1900 8
1901 8
1902 13
1903 24
1904 12
1905 25
1906 10
1907 11
1908 12
1909 3
1910 6
1911 13
1912 14
1913 9
1914 10
1915 11
1916 22
1917 13
1918 12
1919 19
1920 10
1921 15
1922 18
1923 18
1924 17
1925 23
1926 25
1927 25
1928 23
1929 20
1930 20
1931 13
1932 10
1933 13
1934 12
1935 4
1936 10
1937 11
1938 7
1939 9
1940 8
1941 5
1942 6
1943 7
1944 17
1945 872
1946 2368
1947 2004
1948 2196
1949 1345
1950 372
1951 3061
1952 5784
1953 7236
1954 8394
1955 9570
1956 10230
1957 10467
1958 9591
1959 10552
1960 11900
1961 12721
1962 8595
1963 1424
1964 2914
1965 16136
1966 30230
1967 37650
1968 44610
1969 47980
1970 50558
1971 53847
1972 56448
1973 58518
1974 62908
1975 62815
1976 62284
1977 65608
1978 69969
1979 74205
1980 74654
1981 78378
1982 83617
1983 89072
1984 94197
1985 99304
1986 102344
1987 109902
1988 118459
1989 128489
1990 137457
1991 141758
1992 145510
1993 150929
1994 156127
1995 162380
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1998 184057
1999 191064
2000 204557
2001 212849
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2004 248707
2005 270304
2006 289925
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2008 321105
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2015 411580
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Showing results for causal
Search for Caus L instead (3 results)
Causal relationship between gut microbiota and cancers: a two-sample Mendelian randomisation study.
Long Y, Tang L, Zhou Y, Zhao S, Zhu H. Long Y, et al. BMC Med. 2023 Feb 21;21(1):66. doi: 10.1186/s12916-023-02761-6. BMC Med. 2023. PMID: 36810112 Free PMC article.
We then performed two-sample Mendelian randomisation (MR) to determine whether the gut microbiota is causally associated with eight cancer types. Furthermore, we performed a bi-directional MR analysis to examine the direction of the causal relations. RESULTS: We ide …
We then performed two-sample Mendelian randomisation (MR) to determine whether the gut microbiota is causally associated with eight c …
Causation and causal inference in epidemiology.
Rothman KJ, Greenland S. Rothman KJ, et al. Am J Public Health. 2005;95 Suppl 1:S144-50. doi: 10.2105/AJPH.2004.059204. Am J Public Health. 2005. PMID: 16030331
Concepts of cause and causal inference are largely self-taught from early learning experiences. ...Philosophers agree that causal propositions cannot be proved, and find flaws or practical limitations in all philosophies of causal inference. ...
Concepts of cause and causal inference are largely self-taught from early learning experiences. ...Philosophers agree that causal …
Causal Directed Acyclic Graphs.
Lipsky AM, Greenland S. Lipsky AM, et al. JAMA. 2022 Mar 15;327(11):1083-1084. doi: 10.1001/jama.2022.1816. JAMA. 2022. PMID: 35226050 No abstract available.
Causal reductionism and causal structures.
Grasso M, Albantakis L, Lang JP, Tononi G. Grasso M, et al. Nat Neurosci. 2021 Oct;24(10):1348-1355. doi: 10.1038/s41593-021-00911-8. Epub 2021 Sep 23. Nat Neurosci. 2021. PMID: 34556868 Review.
Due to its intuitive appeal, causal reductionism is prevalent in neuroscience: once all neurons have been caused to fire or not to fire, it seems that causally there is nothing left to be accounted for. ...To that end, we outline an explicit, operational approach to …
Due to its intuitive appeal, causal reductionism is prevalent in neuroscience: once all neurons have been caused to fire or not to fi …
Causal inference in drug discovery and development.
Michoel T, Zhang JD. Michoel T, et al. Drug Discov Today. 2023 Oct;28(10):103737. doi: 10.1016/j.drudis.2023.103737. Epub 2023 Aug 15. Drug Discov Today. 2023. PMID: 37591410 Free article. Review.
To discover new drugs is to seek and to prove causality. As an emerging approach leveraging human knowledge and creativity, data, and machine intelligence, causal inference holds the promise of reducing cognitive bias and improving decision-making in drug discovery. …
To discover new drugs is to seek and to prove causality. As an emerging approach leveraging human knowledge and creativity, data, and …
Causal effects of gut microbiota on the risk of chronic kidney disease: a Mendelian randomization study.
Luo M, Cai J, Luo S, Hong X, Xu L, Lin H, Chen X, Fu W. Luo M, et al. Front Cell Infect Microbiol. 2023 Mar 31;13:1142140. doi: 10.3389/fcimb.2023.1142140. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37065213 Free PMC article.
BACKGROUND: Previous studies have reported that gut microbiota is associated with an increased risk of chronic kidney disease (CKD) progression. However, whether gut microbiota has a causal effect on the development of CKD has not been revealed. Thus, we aimed to analyze t …
BACKGROUND: Previous studies have reported that gut microbiota is associated with an increased risk of chronic kidney disease (CKD) progress …
Mendelian randomization analyses support causal relationships between brain imaging-derived phenotypes and risk of psychiatric disorders.
Guo J, Yu K, Dong SS, Yao S, Rong Y, Wu H, Zhang K, Jiang F, Chen YX, Guo Y, Yang TL. Guo J, et al. Nat Neurosci. 2022 Nov;25(11):1519-1527. doi: 10.1038/s41593-022-01174-7. Epub 2022 Oct 10. Nat Neurosci. 2022. PMID: 36216997
Observational studies have reported the correlations between brain imaging-derived phenotypes (IDPs) and psychiatric disorders; however, whether the relationships are causal is uncertain. We conducted bidirectional two-sample Mendelian randomization (MR) analyses to explor …
Observational studies have reported the correlations between brain imaging-derived phenotypes (IDPs) and psychiatric disorders; however, whe …
The causal role of gut microbiota in development of osteoarthritis.
Yu XH, Yang YQ, Cao RR, Bo L, Lei SF. Yu XH, et al. Osteoarthritis Cartilage. 2021 Dec;29(12):1741-1750. doi: 10.1016/j.joca.2021.08.003. Epub 2021 Aug 21. Osteoarthritis Cartilage. 2021. PMID: 34425228 Free article.
OBJECTIVE: There is considerable evidence for relationship between gut microbiota and osteoarthritis (OA), but no studies have investigated their causal relationship. METHOD: This study utilized large-scale genome-wide association studies (GWAS) summary statistics to evalu …
OBJECTIVE: There is considerable evidence for relationship between gut microbiota and osteoarthritis (OA), but no studies have investigated …
Causal factors underlying diabetes risk informed by Mendelian randomisation analysis: evidence, opportunities and challenges.
Yuan S, Merino J, Larsson SC. Yuan S, et al. Diabetologia. 2023 May;66(5):800-812. doi: 10.1007/s00125-023-05879-7. Epub 2023 Feb 14. Diabetologia. 2023. PMID: 36786839 Free PMC article. Review.
Despite the genetic influence on type 1 diabetes, few MR studies have been conducted to identify causal exposures or molecular processes leading to increased disease risk. In type 2 diabetes, MR analyses support causal associations of somatic, mental and lifestyle f …
Despite the genetic influence on type 1 diabetes, few MR studies have been conducted to identify causal exposures or molecular proces …
Causal relationships between CD25 on immune cells and hip osteoarthritis.
Luo H, Zhu Y, Guo B, Ruan Z, Liu Z, Fan Z, Zhao S. Luo H, et al. Front Immunol. 2023 Sep 4;14:1247710. doi: 10.3389/fimmu.2023.1247710. eCollection 2023. Front Immunol. 2023. PMID: 37731506 Free PMC article.
OBJECTIVES: Previous research has indicated a potential association between immune factors and osteoarthritis (OA), but the causal relationship between CD25 expression on immune cells and hip OA remains enigmatic. ...These traits are specifically related to CD4(+)CD25(+) T …
OBJECTIVES: Previous research has indicated a potential association between immune factors and osteoarthritis (OA), but the causal re …
10,870,614 results
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