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Broad neutralization of SARS-related viruses by human monoclonal antibodies.
Wec AZ, Wrapp D, Herbert AS, Maurer DP, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, Champney E, Burnina I, Brown M, Lin S, Sinclair M, Johnson C, Pudi S, Bortz R 3rd, Wirchnianski AS, Laudermilch E, Florez C, Fels JM, O'Brien CM, Graham BS, Nemazee D, Burton DR, Baric RS, Voss JE, Chandran K, Dye JM, McLellan JS, Walker LM. Wec AZ, et al. Among authors: champney e. Science. 2020 Aug 7;369(6504):731-736. doi: 10.1126/science.abc7424. Epub 2020 Jun 15. Science. 2020. PMID: 32540900 Free PMC article.
Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein.
Wec AZ, Wrapp D, Herbert AS, Maurer D, Haslwanter D, Sakharkar M, Jangra RK, Dieterle ME, Lilov A, Huang D, Tse LV, Johnson NV, Hsieh CL, Wang N, Nett JH, Champney E, Burnina I, Brown M, Lin S, Sinclair M, Johnson C, Pudi S, Bortz R 3rd, Wirchnianski AS, Laudermilch E, Florez C, Fels JM, O'Brien CM, Graham BS, Nemazee D, Burton DR, Baric RS, Voss JE, Chandran K, Dye JM, McLellan JS, Walker LM. Wec AZ, et al. Among authors: champney e. bioRxiv [Preprint]. 2020 May 16:2020.05.15.096511. doi: 10.1101/2020.05.15.096511. bioRxiv. 2020. PMID: 32511337 Free PMC article. Preprint.
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers.
Schmidt P, Narayan K, Li Y, Kaku CI, Brown ME, Champney E, Geoghegan JC, Vásquez M, Krauland EM, Yockachonis T, Bai S, Gunn BM, Cammarata A, Rubino CM, Ambrose P, Walker LM. Schmidt P, et al. Among authors: champney e. Sci Transl Med. 2023 Mar 22;15(688):eadg2783. doi: 10.1126/scitranslmed.adg2783. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947596 Free article.
Evolution of antibody immunity following Omicron BA.1 breakthrough infection.
Kaku CI, Starr TN, Zhou P, Dugan HL, Khalifé P, Song G, Champney ER, Mielcarz DW, Geoghegan JC, Burton DR, Andrabi R, Bloom JD, Walker LM. Kaku CI, et al. Among authors: champney er. Nat Commun. 2023 May 12;14(1):2751. doi: 10.1038/s41467-023-38345-4. Nat Commun. 2023. PMID: 37173311 Free PMC article.
Crimean-Congo Hemorrhagic Fever Survivors Elicit Protective Non-Neutralizing Antibodies that Target 11 Overlapping Regions on Viral Glycoprotein GP38.
Shin OS, Monticelli SR, Hjorth CK, Hornet V, Doyle M, Abelson D, Kuehne AI, Wang A, Bakken RR, Mishra A, Middlecamp M, Champney E, Stuart L, Maurer DP, Li J, Berrigan J, Barajas J, Balinandi S, Lutwama JJ, Lobel L, Zeitlin L, Walker LM, Dye JM, Chandran K, Herbert AS, Pauli NT, McLellan JS. Shin OS, et al. Among authors: champney e. bioRxiv [Preprint]. 2024 Mar 6:2024.03.02.583110. doi: 10.1101/2024.03.02.583110. bioRxiv. 2024. PMID: 38496658 Free PMC article. Preprint.
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers.
Schmidt P, Narayan K, Li Y, Kaku C, Brown M, Champney E, Geoghegan J, Vasquez M, Krauland E, Yockachonis T, Bai S, Gunn B, Cammarata A, Rubino C, Walker LM. Schmidt P, et al. Among authors: champney e. medRxiv [Preprint]. 2022 Oct 19:2022.10.18.22281172. doi: 10.1101/2022.10.18.22281172. medRxiv. 2022. PMID: 36299436 Free PMC article. Updated. Preprint.
Evolution of antibody immunity following Omicron BA.1 breakthrough infection.
Kaku CI, Starr TN, Zhou P, Dugan HL, Khalifé P, Song G, Champney ER, Mielcarz DW, Geoghegan JC, Burton DR, Raiees A, Bloom JD, Walker LM. Kaku CI, et al. Among authors: champney er. bioRxiv [Preprint]. 2022 Sep 22:2022.09.21.508922. doi: 10.1101/2022.09.21.508922. bioRxiv. 2022. PMID: 36172124 Free PMC article. Updated. Preprint.