Chen JY - Search Results

1

Cyclic Immunofluorescence (CycIF), A Highly Multiplexed Method for Single-cell Imaging.

Lin JR, Fallahi-Sichani M, Chen JY, Sorger PK. Lin JR, et al. Among authors: chen jy. Curr Protoc Chem Biol. 2016 Dec 7;8(4):251-264. doi: 10.1002/cpch.14. Curr Protoc Chem Biol. 2016. PMID: 27925668 Free PMC article.

2

SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis.

Lin JR, Zeman MK, Chen JY, Yee MC, Cimprich KA. Lin JR, et al. Among authors: chen jy. Mol Cell. 2011 Apr 22;42(2):237-49. doi: 10.1016/j.molcel.2011.02.026. Epub 2011 Mar 10. Mol Cell. 2011. PMID: 21396873 Free PMC article.

3

A two-dimensional ERK-AKT signaling code for an NGF-triggered cell-fate decision.

Chen JY, Lin JR, Cimprich KA, Meyer T. Chen JY, et al. Mol Cell. 2012 Jan 27;45(2):196-209. doi: 10.1016/j.molcel.2011.11.023. Epub 2011 Dec 28. Mol Cell. 2012. PMID: 22206868 Free PMC article.

4

Dosage of Dyrk1a shifts cells within a p21-cyclin D1 signaling map to control the decision to enter the cell cycle.

Chen JY, Lin JR, Tsai FC, Meyer T. Chen JY, et al. Mol Cell. 2013 Oct 10;52(1):87-100. doi: 10.1016/j.molcel.2013.09.009. Mol Cell. 2013. PMID: 24119401 Free PMC article.

5

Torin2 Exploits Replication and Checkpoint Vulnerabilities to Cause Death of PI3K-Activated Triple-Negative Breast Cancer Cells.

Chopra SS, Jenney A, Palmer A, Niepel M, Chung M, Mills C, Sivakumaren SC, Liu Q, Chen JY, Yapp C, Asara JM, Gray NS, Sorger PK. Chopra SS, et al. Among authors: chen jy. Cell Syst. 2020 Jan 22;10(1):66-81.e11. doi: 10.1016/j.cels.2019.11.001. Epub 2019 Dec 4. Cell Syst. 2020. PMID: 31812693 Free PMC article.

6

Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity.

Melms JC, Vallabhaneni S, Mills CE, Yapp C, Chen JY, Morelli E, Waszyk P, Kumar S, Deming D, Moret N, Rodriguez S, Subramanian K, Rogava M, Cartwright ANR, Luoma A, Mei S, Brinker TJ, Miller DM, Spektor A, Schadendorf D, Riggi N, Wucherpfennig KW, Sorger PK, Izar B. Melms JC, et al. Among authors: chen jy. Cancer Res. 2020 Feb 15;80(4):798-810. doi: 10.1158/0008-5472.CAN-19-2330. Epub 2019 Dec 27. Cancer Res. 2020. PMID: 31882401 Free PMC article.

7

Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells.

Gerosa L, Chidley C, Fröhlich F, Sanchez G, Lim SK, Muhlich J, Chen JY, Vallabhaneni S, Baker GJ, Schapiro D, Atanasova MI, Chylek LA, Shi T, Yi L, Nicora CD, Claas A, Ng TSC, Kohler RH, Lauffenburger DA, Weissleder R, Miller MA, Qian WJ, Wiley HS, Sorger PK. Gerosa L, et al. Among authors: chen jy. Cell Syst. 2020 Nov 18;11(5):478-494.e9. doi: 10.1016/j.cels.2020.10.002. Epub 2020 Oct 27. Cell Syst. 2020. PMID: 33113355 Free PMC article.

8

Multi-range ERK responses shape the proliferative trajectory of single cells following oncogene induction.

Chen JY, Hug C, Reyes J, Tian C, Gerosa L, Fröhlich F, Ponsioen B, Snippert HJG, Spencer SL, Jambhekar A, Sorger PK, Lahav G. Chen JY, et al. Cell Rep. 2023 Mar 28;42(3):112252. doi: 10.1016/j.celrep.2023.112252. Epub 2023 Mar 14. Cell Rep. 2023. PMID: 36920903 Free PMC article.

9

Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest.

Reyes J, Chen JY, Stewart-Ornstein J, Karhohs KW, Mock CS, Lahav G. Reyes J, et al. Among authors: chen jy. Mol Cell. 2018 Aug 16;71(4):581-591.e5. doi: 10.1016/j.molcel.2018.06.031. Epub 2018 Jul 26. Mol Cell. 2018. PMID: 30057196 Free PMC article.

10

Fully unsupervised symmetry-based mitosis detection in time-lapse cell microscopy.

Gilad T, Reyes J, Chen JY, Lahav G, Riklin Raviv T. Gilad T, et al. Among authors: chen jy. Bioinformatics. 2019 Aug 1;35(15):2644-2653. doi: 10.1093/bioinformatics/bty1034. Bioinformatics. 2019. PMID: 30590471 Free PMC article.

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