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A Dual-Antigen Enzyme-Linked Immunosorbent Assay Allows the Assessment of Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Seroprevalence in a Low-Transmission Setting.
Hicks SM, Pohl K, Neeman T, McNamara HA, Parsons KM, He JS, Ali SA, Nazir S, Rowntree LC, Nguyen THO, Kedzierska K, Doolan DL, Vinuesa CG, Cook MC, Coatsworth N, Myles PS, Kurth F, Sander LE, Mann GJ, Gruen RL, George AJ, Gardiner EE, Cockburn IA; SARS-CoV-2 Testing in Elective Surgery Collaborators. Hicks SM, et al. Among authors: cockburn ia. J Infect Dis. 2021 Jan 4;223(1):10-14. doi: 10.1093/infdis/jiaa623. J Infect Dis. 2021. PMID: 33009908 Free PMC article.
TFH-derived dopamine accelerates productive synapses in germinal centres.
Papa I, Saliba D, Ponzoni M, Bustamante S, Canete PF, Gonzalez-Figueroa P, McNamara HA, Valvo S, Grimbaldeston M, Sweet RA, Vohra H, Cockburn IA, Meyer-Hermann M, Dustin ML, Doglioni C, Vinuesa CG. Papa I, et al. Among authors: cockburn ia. Nature. 2017 Jul 20;547(7663):318-323. doi: 10.1038/nature23013. Epub 2017 Jul 12. Nature. 2017. PMID: 28700579 Free PMC article.
Up-regulation of LFA-1 allows liver-resident memory T cells to patrol and remain in the hepatic sinusoids.
McNamara HA, Cai Y, Wagle MV, Sontani Y, Roots CM, Miosge LA, O'Connor JH, Sutton HJ, Ganusov VV, Heath WR, Bertolino P, Goodnow CG, Parish IA, Enders A, Cockburn IA. McNamara HA, et al. Among authors: cockburn ia. Sci Immunol. 2017 Mar;2(9):eaaj1996. doi: 10.1126/sciimmunol.aaj1996. Epub 2017 Mar 17. Sci Immunol. 2017. PMID: 28707003 Free PMC article.
T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein.
Fisher CR, Sutton HJ, Kaczmarski JA, McNamara HA, Clifton B, Mitchell J, Cai Y, Dups JN, D'Arcy NJ, Singh M, Chuah A, Peat TS, Jackson CJ, Cockburn IA. Fisher CR, et al. Among authors: cockburn ia. PLoS Pathog. 2017 Jul 31;13(7):e1006469. doi: 10.1371/journal.ppat.1006469. eCollection 2017 Jul. PLoS Pathog. 2017. PMID: 28759640 Free PMC article.
HIV Immunogens: Affinity Is Key.
Prabhu S, Cockburn IA, Vinuesa CG. Prabhu S, et al. Among authors: cockburn ia. Immunity. 2018 Jan 16;48(1):11-13. doi: 10.1016/j.immuni.2018.01.002. Immunity. 2018. PMID: 29343432 Free article.
Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response.
McNamara HA, Idris AH, Sutton HJ, Vistein R, Flynn BJ, Cai Y, Wiehe K, Lyke KE, Chatterjee D, Kc N, Chakravarty S, Lee Sim BK, Hoffman SL, Bonsignori M, Seder RA, Cockburn IA. McNamara HA, et al. Among authors: cockburn ia. Cell Host Microbe. 2020 Oct 7;28(4):572-585.e7. doi: 10.1016/j.chom.2020.07.001. Epub 2020 Jul 21. Cell Host Microbe. 2020. PMID: 32697938 Free article.
Atypical B cells are part of an alternative lineage of B cells that participates in responses to vaccination and infection in humans.
Sutton HJ, Aye R, Idris AH, Vistein R, Nduati E, Kai O, Mwacharo J, Li X, Gao X, Andrews TD, Koutsakos M, Nguyen THO, Nekrasov M, Milburn P, Eltahla A, Berry AA, Kc N, Chakravarty S, Sim BKL, Wheatley AK, Kent SJ, Hoffman SL, Lyke KE, Bejon P, Luciani F, Kedzierska K, Seder RA, Ndungu FM, Cockburn IA. Sutton HJ, et al. Among authors: cockburn ia. Cell Rep. 2021 Feb 9;34(6):108684. doi: 10.1016/j.celrep.2020.108684. Cell Rep. 2021. PMID: 33567273 Free PMC article. Clinical Trial.
A Point Mutation in IKAROS ZF1 Causes a B Cell Deficiency in Mice.
Boast B, Miosge LA, Kuehn HS, Cho V, Athanasopoulos V, McNamara HA, Sontani Y, Mei Y, Howard D, Sutton HJ, Omari SA, Yu Z, Nasreen M, Andrews TD, Cockburn IA, Goodnow CC, Rosenzweig SD, Enders A. Boast B, et al. Among authors: cockburn ia. J Immunol. 2021 Apr 1;206(7):1505-1514. doi: 10.4049/jimmunol.1901464. Epub 2021 Mar 3. J Immunol. 2021. PMID: 33658297 Free PMC article.
70 results