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Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels.
Siskind LJ, Feinstein L, Yu T, Davis JS, Jones D, Choi J, Zuckerman JE, Tan W, Hill RB, Hardwick JM, Colombini M. Siskind LJ, et al. Among authors: colombini m. J Biol Chem. 2008 Mar 14;283(11):6622-30. doi: 10.1074/jbc.M706115200. Epub 2008 Jan 2. J Biol Chem. 2008. PMID: 18171672 Free PMC article.
We reported previously that at physiologically relevant levels, ceramides form stable channels in mitochondrial outer membranes capable of passing the largest proteins known to exit mitochondria during apoptosis (Siskind, L. J., Kolesnick, R. N., and Colombini, M. ( …
We reported previously that at physiologically relevant levels, ceramides form stable channels in mitochondrial outer membranes capable of p …
Ceramide channels increase the permeability of the mitochondrial outer membrane to small proteins.
Siskind LJ, Kolesnick RN, Colombini M. Siskind LJ, et al. Among authors: colombini m. J Biol Chem. 2002 Jul 26;277(30):26796-803. doi: 10.1074/jbc.M200754200. Epub 2002 May 10. J Biol Chem. 2002. PMID: 12006562 Free PMC article.
We have previously reported that C(2)- and C(16)-ceramide, but not dihydroceramide, form large channels in planar membranes (Siskind, L. J., and Colombini, M. (2001) J. Biol. Chem. 275, 38640-38644). Here we show that ceramides do not trigger a cytochrome c secretio …
We have previously reported that C(2)- and C(16)-ceramide, but not dihydroceramide, form large channels in planar membranes (Siskind, L. J., …
341 results