Cox TM - Search Results

1

Eliglustat maintains long-term clinical stability in patients with Gaucher disease type 1 stabilized on enzyme therapy.

Cox TM, Drelichman G, Cravo R, Balwani M, Burrow TA, Martins AM, Lukina E, Rosenbloom B, Goker-Alpan O, Watman N, El-Beshlawy A, Kishnani PS, Pedroso ML, Gaemers SJM, Tayag R, Peterschmitt MJ. Cox TM, et al. Blood. 2017 Apr 27;129(17):2375-2383. doi: 10.1182/blood-2016-12-758409. Epub 2017 Feb 6. Blood. 2017. PMID: 28167660 Free PMC article. Clinical Trial.

2

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.

Cox T, Lachmann R, Hollak C, Aerts J, van Weely S, Hrebícek M, Platt F, Butters T, Dwek R, Moyses C, Gow I, Elstein D, Zimran A. Cox T, et al. Lancet. 2000 Apr 29;355(9214):1481-5. doi: 10.1016/S0140-6736(00)02161-9. Lancet. 2000. PMID: 10801168 Clinical Trial.

3

Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention.

Boot RG, Verhoek M, de Fost M, Hollak CE, Maas M, Bleijlevens B, van Breemen MJ, van Meurs M, Boven LA, Laman JD, Moran MT, Cox TM, Aerts JM. Boot RG, et al. Among authors: cox tm. Blood. 2004 Jan 1;103(1):33-9. doi: 10.1182/blood-2003-05-1612. Epub 2003 Sep 11. Blood. 2004. PMID: 12969956 Free article.

4

Clinical evaluation of chemokine and enzymatic biomarkers of Gaucher disease.

Deegan PB, Moran MT, McFarlane I, Schofield JP, Boot RG, Aerts JM, Cox TM. Deegan PB, et al. Among authors: cox tm. Blood Cells Mol Dis. 2005 Sep-Oct;35(2):259-67. doi: 10.1016/j.bcmd.2005.05.005. Blood Cells Mol Dis. 2005. PMID: 16125420

5

Guidelines for the restart of imiglucerase in patients with Gaucher disease: recommendations from the European Working Group on Gaucher disease.

Hollak CE, Aerts JM, Belmatoug N, Bembi B, Bodamer O, Cappellini D, Collin-Histed T, Cox TM, Deegan P, Giraldo P, Hughes D, Lukina E, Manuel J, Michelakakis H, Di Rocco M, Vellodi A, Zimran A. Hollak CE, et al. Among authors: cox tm. Blood Cells Mol Dis. 2010 Mar-Apr;44(2):86-7. doi: 10.1016/j.bcmd.2009.12.002. Blood Cells Mol Dis. 2010. PMID: 20022271 No abstract available.

6

A validated disease severity scoring system for adults with type 1 Gaucher disease.

Weinreb NJ, Cappellini MD, Cox TM, Giannini EH, Grabowski GA, Hwu WL, Mankin H, Martins AM, Sawyer C, vom Dahl S, Yeh MS, Zimran A. Weinreb NJ, et al. Among authors: cox tm. Genet Med. 2010 Jan;12(1):44-51. doi: 10.1097/GIM.0b013e3181c39194. Genet Med. 2010. PMID: 20027115 Free article.

7

Eliglustat tartrate, an orally active glucocerebroside synthase inhibitor for the potential treatment of Gaucher disease and other lysosomal storage diseases.

Cox TM. Cox TM. Curr Opin Investig Drugs. 2010 Oct;11(10):1169-81. Curr Opin Investig Drugs. 2010. PMID: 20872320 Review.

8

Potential biomarkers of osteonecrosis in Gaucher disease.

Pavlova EV, Deegan PB, Tindall J, McFarlane I, Mehta A, Hughes D, Wraith JE, Cox TM. Pavlova EV, et al. Among authors: cox tm. Blood Cells Mol Dis. 2011 Jan 15;46(1):27-33. doi: 10.1016/j.bcmd.2010.10.010. Epub 2010 Nov 13. Blood Cells Mol Dis. 2011. PMID: 21075651

9

Evaluation of miglustat as maintenance therapy after enzyme therapy in adults with stable type 1 Gaucher disease: a prospective, open-label non-inferiority study.

Cox TM, Amato D, Hollak CE, Luzy C, Silkey M, Giorgino R, Steiner RD; Miglustat Maintenance Study Group. Cox TM, et al. Orphanet J Rare Dis. 2012 Dec 27;7:102. doi: 10.1186/1750-1172-7-102. Orphanet J Rare Dis. 2012. PMID: 23270487 Free PMC article.

10

Inhibition of UDP-glucosylceramide synthase in mice prevents Gaucher disease-associated B-cell malignancy.

Pavlova EV, Archer J, Wang S, Dekker N, Aerts JM, Karlsson S, Cox TM. Pavlova EV, et al. Among authors: cox tm. J Pathol. 2015 Jan;235(1):113-24. doi: 10.1002/path.4452. J Pathol. 2015. PMID: 25256118

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