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676 results

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Phase I study of vismodegib in children with recurrent or refractory medulloblastoma: a pediatric brain tumor consortium study.
Gajjar A, Stewart CF, Ellison DW, Kaste S, Kun LE, Packer RJ, Goldman S, Chintagumpala M, Wallace D, Takebe N, Boyett JM, Gilbertson RJ, Curran T. Gajjar A, et al. Among authors: curran t. Clin Cancer Res. 2013 Nov 15;19(22):6305-12. doi: 10.1158/1078-0432.CCR-13-1425. Epub 2013 Sep 27. Clin Cancer Res. 2013. PMID: 24077351 Free PMC article. Clinical Trial.
Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.
Robinson GW, Orr BA, Wu G, Gururangan S, Lin T, Qaddoumi I, Packer RJ, Goldman S, Prados MD, Desjardins A, Chintagumpala M, Takebe N, Kaste SC, Rusch M, Allen SJ, Onar-Thomas A, Stewart CF, Fouladi M, Boyett JM, Gilbertson RJ, Curran T, Ellison DW, Gajjar A. Robinson GW, et al. Among authors: curran t. J Clin Oncol. 2015 Aug 20;33(24):2646-54. doi: 10.1200/JCO.2014.60.1591. Epub 2015 Jul 13. J Clin Oncol. 2015. PMID: 26169613 Free PMC article. Clinical Trial.
A molecular fingerprint for medulloblastoma.
Lee Y, Miller HL, Jensen P, Hernan R, Connelly M, Wetmore C, Zindy F, Roussel MF, Curran T, Gilbertson RJ, McKinnon PJ. Lee Y, et al. Among authors: curran t. Cancer Res. 2003 Sep 1;63(17):5428-37. Cancer Res. 2003. PMID: 14500378
Radial glia cells are candidate stem cells of ependymoma.
Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, Macdonald T, Rutka J, Guha A, Gajjar A, Curran T, Gilbertson RJ. Taylor MD, et al. Among authors: curran t. Cancer Cell. 2005 Oct;8(4):323-35. doi: 10.1016/j.ccr.2005.09.001. Cancer Cell. 2005. PMID: 16226707 Free article.
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.
Uziel T, Zindy F, Xie S, Lee Y, Forget A, Magdaleno S, Rehg JE, Calabrese C, Solecki D, Eberhart CG, Sherr SE, Plimmer S, Clifford SC, Hatten ME, McKinnon PJ, Gilbertson RJ, Curran T, Sherr CJ, Roussel MF. Uziel T, et al. Among authors: curran t. Genes Dev. 2005 Nov 15;19(22):2656-67. doi: 10.1101/gad.1368605. Epub 2005 Oct 31. Genes Dev. 2005. PMID: 16260494 Free PMC article.
The genetic landscape of the childhood cancer medulloblastoma.
Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, Smith DR, Gerhard DS, Fults DW, VandenBerg S, Berger MS, Marie SK, Shinjo SM, Clara C, Phillips PC, Minturn JE, Biegel JA, Judkins AR, Resnick AC, Storm PB, Curran T, He Y, Rasheed BA, Friedman HS, Keir ST, McLendon R, Northcott PA, Taylor MD, Burger PC, Riggins GJ, Karchin R, Parmigiani G, Bigner DD, Yan H, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE. Parsons DW, et al. Among authors: curran t. Science. 2011 Jan 28;331(6016):435-9. doi: 10.1126/science.1198056. Epub 2010 Dec 16. Science. 2011. PMID: 21163964 Free PMC article.
676 results