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The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways.
D'Amico M, Hulit J, Amanatullah DF, Zafonte BT, Albanese C, Bouzahzah B, Fu M, Augenlicht LH, Donehower LA, Takemaru K, Moon RT, Davis R, Lisanti MP, Shtutman M, Zhurinsky J, Ben-Ze'ev A, Troussard AA, Dedhar S, Pestell RG. D'Amico M, et al. J Biol Chem. 2000 Oct 20;275(42):32649-57. doi: 10.1074/jbc.M000643200. J Biol Chem. 2000. PMID: 10915780 Free article.
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway.
Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R, Ben-Ze'ev A. Shtutman M, et al. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5522-7. doi: 10.1073/pnas.96.10.5522. Proc Natl Acad Sci U S A. 1999. PMID: 10318916 Free PMC article.
Inhibition of cyclin D1 gene transcription by Brg-1.
Rao M, Casimiro MC, Lisanti MP, D'Amico M, Wang C, Shirley LA, Leader JE, Liu M, Stallcup M, Engel DA, Murphy DJ, Pestell RG. Rao M, et al. Cell Cycle. 2008 Mar 1;7(5):647-55. doi: 10.4161/cc.7.5.5446. Epub 2007 Dec 12. Cell Cycle. 2008. PMID: 18239461
The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis.
D'Amico M, Wu K, Di Vizio D, Reutens AT, Stahl M, Fu M, Albanese C, Russell RG, Muller WJ, White M, Negassa A, Lee HW, DePinho RA, Pestell RG. D'Amico M, et al. Cancer Res. 2003 Jun 15;63(12):3395-402. Cancer Res. 2003. PMID: 12810676
742 results