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Page 1
Showing results for damgo ci
Search for Dambo CI instead (2 results)
Optimization binding studies of opioid receptors, saturation and competition, using [(3)H]-DAMGO.
Khoramjouy M, Ahmadi F, Faizi M, Shahhosseini S. Khoramjouy M, et al. Pharmacol Rep. 2021 Oct;73(5):1390-1395. doi: 10.1007/s43440-021-00265-9. Epub 2021 Apr 19. Pharmacol Rep. 2021. PMID: 33871815
METHODS: We used the midbrain and brainstem of naltrexone-treated rats as a source of -opioid receptors, and [(3)H]-DAMGO as the radioligand. Naloxone was also used to determine non-specific binding. A given amount of membrane protein was incubated with an increasing amoun …
METHODS: We used the midbrain and brainstem of naltrexone-treated rats as a source of -opioid receptors, and [(3)H]-DAMGO as the radi …
Age-related changes in peripheral nociceptor function.
Jennings EM, Sullivan LC, Jamshidi RJ, LoCoco PM, Smith HR, Chavera TS, Berg KA, Clarke WP. Jennings EM, et al. Neuropharmacology. 2022 Sep 15;216:109187. doi: 10.1016/j.neuropharm.2022.109187. Epub 2022 Jul 12. Neuropharmacology. 2022. PMID: 35835212
Intraplantar injection of TRP channel activators, capsaicin (TRPV1), mustard oil (TRPA1) and menthol (TRPM8) each resulted in greater mechanical allodynia in aged versus young rats and capsaicin-induced heat allodynia was also greater in aged rats. A treatment-induced …
Intraplantar injection of TRP channel activators, capsaicin (TRPV1), mustard oil (TRPA1) and menthol (TRPM8) each resulted in greater mechan …
Brief Opioid Exposure Paradoxically Augments Primary Afferent Input to Spinal Excitatory Neurons via α2δ-1-Dependent Presynaptic NMDA Receptors.
Chen SR, Chen H, Jin D, Pan HL. Chen SR, et al. J Neurosci. 2022 Dec 14;42(50):9315-9329. doi: 10.1523/JNEUROSCI.1704-22.2022. Epub 2022 Nov 15. J Neurosci. 2022. PMID: 36379705 Free PMC article.
Spinal cord slice recordings revealed that -opioid receptor (MOR) stimulation with DAMGO initially inhibited dorsal root-evoked EPSCs in 87% VGluT2 neurons and subsequently induced LTP in 49% of these neurons. ...Furthermore, conditional Grin1 knockout in dorsal roo …
Spinal cord slice recordings revealed that -opioid receptor (MOR) stimulation with DAMGO initially inhibited dorsal root-evoked EPSCs …
Fentanyl induces autism-like behaviours in mice by hypermethylation of the glutamate receptor gene Grin2b.
Sheng Z, Liu Q, Cheng C, Li M, Barash J, Kofke WA, Shen Y, Xie Z. Sheng Z, et al. Br J Anaesth. 2022 Oct;129(4):544-554. doi: 10.1016/j.bja.2022.04.027. Epub 2022 Jun 11. Br J Anaesth. 2022. PMID: 35697546 Free article.
In the specific activation and rescue experiments, we injected the mu opioid receptor agonist [D-Ala,(2) N-MePhe,(4) Gly-ol]-enkephalin (DAMGO) or Grin2b overexpression lentivirus into the anterior cingulate cortex of male mice. ...The mu-opioid receptor antagonist …
In the specific activation and rescue experiments, we injected the mu opioid receptor agonist [D-Ala,(2) N-MePhe,(4) Gly-ol]-enkephalin …
CI-977, a novel and selective agonist for the kappa-opioid receptor.
Hunter JC, Leighton GE, Meecham KG, Boyle SJ, Horwell DC, Rees DC, Hughes J. Hunter JC, et al. Br J Pharmacol. 1990 Sep;101(1):183-9. doi: 10.1111/j.1476-5381.1990.tb12110.x. Br J Pharmacol. 1990. PMID: 2178014 Free PMC article.
In a radioligand binding studies, with guinea-pig forebrain homogenates, CI-977 bound with high affinity to [3H]-U69593-labelled kappa-sites (Ki = 0.11 nM) but with low affinity to [3H]-[D-Ala2, MePhe4, Gly-ol5] enkephalin (DAMGO) labelled mu-sites (Ki = 99 n …
In a radioligand binding studies, with guinea-pig forebrain homogenates, CI-977 bound with high affinity to [3H]-U69593-labelled kapp …
DAMGO and 6beta-glycine substituted 14-O-methyloxymorphone but not morphine show peripheral, preemptive antinociception after systemic administration in a mouse visceral pain model and high intrinsic efficacy in the isolated rat vas deferens.
Al-Khrasani M, Spetea M, Friedmann T, Riba P, Király K, Schmidhammer H, Furst S. Al-Khrasani M, et al. Brain Res Bull. 2007 Oct 19;74(5):369-75. doi: 10.1016/j.brainresbull.2007.07.008. Epub 2007 Jul 30. Brain Res Bull. 2007. PMID: 17845912
HS-731 administered subcutaneously (s.c.) or intracerebroventricularly (i.c.v.) dose-dependently and completely inhibited writhing, being 24-598-fold more potent, depending on the administration route, than two selective MOR agonists, the enkephalin analogue [D-Ala(2),N-Me …
HS-731 administered subcutaneously (s.c.) or intracerebroventricularly (i.c.v.) dose-dependently and completely inhibited writhing, being 24 …
Intra-amygdalar injection of DAMGO: effects on c-Fos levels in brain sites associated with feeding behavior.
Levine AS, Olszewski PK, Mullett MA, Pomonis JD, Grace MK, Kotz CM, Billington CJ. Levine AS, et al. Brain Res. 2004 Jul 23;1015(1-2):9-14. doi: 10.1016/j.brainres.2004.04.039. Brain Res. 2004. PMID: 15223361
We also studied the effect of CeA-injected DAMGO on LiCl-induced increases in c-Fos IR in the amygdala. As was expected, intra-CeA injection of DAMGO increased food intake of rats over a 4-h period. ...We also found that intra-CeA injection of DAMGO, p …
We also studied the effect of CeA-injected DAMGO on LiCl-induced increases in c-Fos IR in the amygdala. As was expected, intra …
DAMGO in the central amygdala alleviates the affective dimension of pain in a rat model of inflammatory hyperalgesia.
Zhang RX, Zhang M, Li A, Pan L, Berman BM, Ren K, Lao L. Zhang RX, et al. Neuroscience. 2013 Nov 12;252:359-66. doi: 10.1016/j.neuroscience.2013.08.030. Epub 2013 Aug 28. Neuroscience. 2013. PMID: 23994597 Free PMC article.
We hypothesized that systemic morphine before a post-conditioning test would more potently attenuate the affective aspect compared to the sensory component and that [d-Ala2-N-Me-Phe4, Gly-ol5]-enkephalin (DAMGO), a mu-selective opioid receptor agonist, injected into …
We hypothesized that systemic morphine before a post-conditioning test would more potently attenuate the affective aspect compared to the se …
Brain region- and sex-specific alterations in DAMGO-stimulated [(35) S]GTPgammaS binding in mice with Oprm1 A112G.
Wang YJ, Huang P, Blendy JA, Liu-Chen LY. Wang YJ, et al. Addict Biol. 2014 May;19(3):354-61. doi: 10.1111/j.1369-1600.2012.00484.x. Epub 2012 Aug 2. Addict Biol. 2014. PMID: 22862850 Free PMC article.
We compared A/A and G/G mice in the MOPR-selective agonist [D-Ala2, N-MePhe4, Gly-ol]-enkephalin (DAMGO)-stimulated [(35) S]GTPgammaS binding in brain regions by autoradiography. ...In the nucleus accumbens (NAc) core, female G/G mice displayed lower DAMGO-st …
We compared A/A and G/G mice in the MOPR-selective agonist [D-Ala2, N-MePhe4, Gly-ol]-enkephalin (DAMGO)-stimulated [(35) S]GT …
Sensitization by ventral pallidal DAMGO: lack of cross-sensitization to morphine.
Rokosik SL, Persons AL, Napier TC. Rokosik SL, et al. Neuroreport. 2013 Feb 13;24(3):152-8. doi: 10.1097/WNR.0b013e32835e11a2. Neuroreport. 2013. PMID: 23337715
Repeated injections of morphine into the ventral pallidum of laboratory rats results in the development and expression of motor sensitization. Although morphine and [D-Ala, N-MePhe, Gly(ol)]-enkephalin (DAMGO) both activate mu-opioid receptors, their influence on re …
Repeated injections of morphine into the ventral pallidum of laboratory rats results in the development and expression of motor sensitizatio …
200 results