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A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo.
Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, van der Marel GA, Dantuma NP, Overkleeft HS. Verdoes M, et al. Among authors: dantuma np. Chem Biol. 2006 Nov;13(11):1217-26. doi: 10.1016/j.chembiol.2006.09.013. Chem Biol. 2006. PMID: 17114003
A transgenic mouse model of the ubiquitin/proteasome system.
Lindsten K, Menéndez-Benito V, Masucci MG, Dantuma NP. Lindsten K, et al. Among authors: dantuma np. Nat Biotechnol. 2003 Aug;21(8):897-902. doi: 10.1038/nbt851. Epub 2003 Jul 20. Nat Biotechnol. 2003. PMID: 12872133
Disease-associated prion protein oligomers inhibit the 26S proteasome.
Kristiansen M, Deriziotis P, Dimcheff DE, Jackson GS, Ovaa H, Naumann H, Clarke AR, van Leeuwen FW, Menéndez-Benito V, Dantuma NP, Portis JL, Collinge J, Tabrizi SJ. Kristiansen M, et al. Among authors: dantuma np. Mol Cell. 2007 Apr 27;26(2):175-88. doi: 10.1016/j.molcel.2007.04.001. Mol Cell. 2007. PMID: 17466621 Free article.
Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment.
Maynard CJ, Böttcher C, Ortega Z, Smith R, Florea BI, Díaz-Hernández M, Brundin P, Overkleeft HS, Li JY, Lucas JJ, Dantuma NP. Maynard CJ, et al. Among authors: dantuma np. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13986-91. doi: 10.1073/pnas.0906463106. Epub 2009 Jul 30. Proc Natl Acad Sci U S A. 2009. PMID: 19666572 Free PMC article.
89 results