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Lack of antiviral activity of darunavir against SARS-CoV-2.
De Meyer S, Bojkova D, Cinatl J, Van Damme E, Buyck C, Van Loock M, Woodfall B, Ciesek S. De Meyer S, et al. Int J Infect Dis. 2020 Aug;97:7-10. doi: 10.1016/j.ijid.2020.05.085. Epub 2020 May 29. Int J Infect Dis. 2020. PMID: 32479865 Free PMC article.
Week 48 Resistance Analyses of the Once-Daily, Single-Tablet Regimen Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) in Adults Living with HIV-1 from the Phase III Randomized AMBER and EMERALD Trials.
Lathouwers E, Wong EY, Brown K, Baugh B, Ghys A, Jezorwski J, Mohsine EG, Van Landuyt E, Opsomer M, De Meyer S; AMBER and EMERALD Study Groups. Lathouwers E, et al. Among authors: de meyer s. AIDS Res Hum Retroviruses. 2020 Jan;36(1):48-57. doi: 10.1089/AID.2019.0111. Epub 2019 Oct 21. AIDS Res Hum Retroviruses. 2020. PMID: 31516033 Free PMC article. Clinical Trial.
Pooled resistance analyses of darunavir once-daily regimens and formulations across 10 clinical studies of treatment-naïve and treatment-experienced patients with human immunodeficiency virus-1 infection.
Lathouwers E, Seyedkazemi S, Luo D, Brown K, De Meyer S, Wong EY. Lathouwers E, et al. Among authors: de meyer s. HIV Res Clin Pract. 2020 Apr-Jun;21(2-3):83-89. doi: 10.1080/25787489.2020.1794439. Epub 2020 Jul 26. HIV Res Clin Pract. 2020. PMID: 32715952
Week 96 resistance analyses of the once-daily, single-tablet regimen (STR) darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in adults living with HIV-1 from the phase 3 randomized AMBER and EMERALD trials.
Lathouwers E, Weinsteiger S, Baugh B, Ghys A, Jezorwski J, Mohsine EG, Van Landuyt E, De Meyer S. Lathouwers E, et al. Among authors: de meyer s. J Med Virol. 2021 Jun;93(6):3985-3990. doi: 10.1002/jmv.26721. Epub 2021 Feb 15. J Med Virol. 2021. PMID: 33300183 Clinical Trial.
In vitro activity of itraconazole against SARS-CoV-2.
Van Damme E, De Meyer S, Bojkova D, Ciesek S, Cinatl J, De Jonghe S, Jochmans D, Leyssen P, Buyck C, Neyts J, Van Loock M. Van Damme E, et al. Among authors: de jonghe s, de meyer s. J Med Virol. 2021 Jul;93(7):4454-4460. doi: 10.1002/jmv.26917. J Med Virol. 2021. PMID: 33666253 Free PMC article.
Development and optimization of a high-throughput screening assay for in vitro anti-SARS-CoV-2 activity: Evaluation of 5676 Phase 1 Passed Structures.
Chiu W, Verschueren L, Van den Eynde C, Buyck C, De Meyer S, Jochmans D, Bojkova D, Ciesek S, Cinatl J, De Jonghe S, Leyssen P, Neyts J, Van Loock M, Van Damme E. Chiu W, et al. Among authors: de jonghe s, de meyer s. J Med Virol. 2022 Jul;94(7):3101-3111. doi: 10.1002/jmv.27683. Epub 2022 Mar 23. J Med Virol. 2022. PMID: 35229317 Free PMC article.
Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
Goethals O, Kaptein SJF, Kesteleyn B, Bonfanti JF, Van Wesenbeeck L, Bardiot D, Verschoor EJ, Verstrepen BE, Fagrouch Z, Putnak JR, Kiemel D, Ackaert O, Straetemans R, Lachau-Durand S, Geluykens P, Crabbe M, Thys K, Stoops B, Lenz O, Tambuyzer L, De Meyer S, Dallmeier K, McCracken MK, Gromowski GD, Rutvisuttinunt W, Jarman RG, Karasavvas N, Touret F, Querat G, de Lamballerie X, Chatel-Chaix L, Milligan GN, Beasley DWC, Bourne N, Barrett ADT, Marchand A, Jonckers THM, Raboisson P, Simmen K, Chaltin P, Bartenschlager R, Bogers WM, Neyts J, Van Loock M. Goethals O, et al. Among authors: de meyer s, de lamballerie x. Nature. 2023 Mar;615(7953):678-686. doi: 10.1038/s41586-023-05790-6. Epub 2023 Mar 15. Nature. 2023. PMID: 36922586 Free PMC article.
291 results