Decher N - Search Results

1

Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.

Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC, Keating MT. Splawski I, et al. Among authors: decher n. Cell. 2004 Oct 1;119(1):19-31. doi: 10.1016/j.cell.2004.09.011. Cell. 2004. PMID: 15454078 Free article.

2

Molecular basis for Kv1.5 channel block: conservation of drug binding sites among voltage-gated K+ channels.

Decher N, Pirard B, Bundis F, Peukert S, Baringhaus KH, Busch AE, Steinmeyer K, Sanguinetti MC. Decher N, et al. J Biol Chem. 2004 Jan 2;279(1):394-400. doi: 10.1074/jbc.M307411200. Epub 2003 Oct 25. J Biol Chem. 2004. PMID: 14578345 Free article.

3

Voltage-dependent gating of hyperpolarization-activated, cyclic nucleotide-gated pacemaker channels: molecular coupling between the S4-S5 and C-linkers.

Decher N, Chen J, Sanguinetti MC. Decher N, et al. J Biol Chem. 2004 Apr 2;279(14):13859-65. doi: 10.1074/jbc.M313704200. Epub 2004 Jan 15. J Biol Chem. 2004. PMID: 14726518 Free article.

4

Novel KChIP2 isoforms increase functional diversity of transient outward potassium currents.

Decher N, Barth AS, Gonzalez T, Steinmeyer K, Sanguinetti MC. Decher N, et al. J Physiol. 2004 Jun 15;557(Pt 3):761-72. doi: 10.1113/jphysiol.2004.066720. Epub 2004 Apr 23. J Physiol. 2004. PMID: 15107477 Free PMC article.

5

Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations.

Splawski I, Timothy KW, Decher N, Kumar P, Sachse FB, Beggs AH, Sanguinetti MC, Keating MT. Splawski I, et al. Among authors: decher n. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8089-96; discussion 8086-8. doi: 10.1073/pnas.0502506102. Epub 2005 Apr 29. Proc Natl Acad Sci U S A. 2005. PMID: 15863612 Free PMC article.

6

Structural basis for competition between drug binding and Kvbeta 1.3 accessory subunit-induced N-type inactivation of Kv1.5 channels.

Decher N, Kumar P, Gonzalez T, Renigunta V, Sanguinetti MC. Decher N, et al. Mol Pharmacol. 2005 Oct;68(4):995-1005. doi: 10.1124/mol.105.011668. Epub 2005 Jul 15. Mol Pharmacol. 2005. PMID: 16024663

7

Binding site of a novel Kv1.5 blocker: a "foot in the door" against atrial fibrillation.

Decher N, Kumar P, Gonzalez T, Pirard B, Sanguinetti MC. Decher N, et al. Mol Pharmacol. 2006 Oct;70(4):1204-11. doi: 10.1124/mol.106.026203. Epub 2006 Jul 11. Mol Pharmacol. 2006. PMID: 16835355

8

Impaired interaction between the slide helix and the C-terminus of Kir2.1: a novel mechanism of Andersen syndrome.

Decher N, Renigunta V, Zuzarte M, Soom M, Heinemann SH, Timothy KW, Keating MT, Daut J, Sanguinetti MC, Splawski I. Decher N, et al. Cardiovasc Res. 2007 Sep 1;75(4):748-57. doi: 10.1016/j.cardiores.2007.05.010. Epub 2007 May 10. Cardiovasc Res. 2007. PMID: 17568571

9

Hyperinsulinemic Hypoglycemia Associated with a Ca_V1.2 Variant with Mixed Gain- and Loss-of-Function Effects.

Kummer S, Rinné S, Seemann G, Bachmann N, Timothy K, Thornton PS, Pillekamp F, Mayatepek E, Bergmann C, Meissner T, Decher N. Kummer S, et al. Among authors: decher n. Int J Mol Sci. 2022 Jul 22;23(15):8097. doi: 10.3390/ijms23158097. Int J Mol Sci. 2022. PMID: 35897673 Free PMC article.

10

Structural determinants of Kvbeta1.3-induced channel inactivation: a hairpin modulated by PIP2.

Decher N, Gonzalez T, Streit AK, Sachse FB, Renigunta V, Soom M, Heinemann SH, Daut J, Sanguinetti MC. Decher N, et al. EMBO J. 2008 Dec 3;27(23):3164-74. doi: 10.1038/emboj.2008.231. Epub 2008 Nov 6. EMBO J. 2008. PMID: 18987637 Free PMC article.

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