Denison MR - Search Results

1

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.

Sheahan TP, Sims AC, Zhou S, Graham RL, Pruijssers AJ, Agostini ML, Leist SR, Schäfer A, Dinnon KH 3rd, Stevens LJ, Chappell JD, Lu X, Hughes TM, George AS, Hill CS, Montgomery SA, Brown AJ, Bluemling GR, Natchus MG, Saindane M, Kolykhalov AA, Painter G, Harcourt J, Tamin A, Thornburg NJ, Swanstrom R, Denison MR, Baric RS. Sheahan TP, et al. Among authors: denison mr. Sci Transl Med. 2020 Apr 29;12(541):eabb5883. doi: 10.1126/scitranslmed.abb5883. Epub 2020 Apr 6. Sci Transl Med. 2020. PMID: 32253226 Free PMC article.

2

Identification and characterization of a serine-like proteinase of the murine coronavirus MHV-A59.

Lu Y, Lu X, Denison MR. Lu Y, et al. Among authors: denison mr. J Virol. 1995 Jun;69(6):3554-9. doi: 10.1128/JVI.69.6.3554-3559.1995. J Virol. 1995. PMID: 7745703 Free PMC article.

3

Intracellular and in vitro-translated 27-kDa proteins contain the 3C-like proteinase activity of the coronavirus MHV-A59.

Lu X, Lu Y, Denison MR. Lu X, et al. Among authors: denison mr. Virology. 1996 Aug 15;222(2):375-82. doi: 10.1006/viro.1996.0434. Virology. 1996. PMID: 8806521 Free PMC article.

4

Mouse hepatitis virus 3C-like protease cleaves a 22-kilodalton protein from the open reading frame 1a polyprotein in virus-infected cells and in vitro.

Lu XT, Sims AC, Denison MR. Lu XT, et al. Among authors: denison mr. J Virol. 1998 Mar;72(3):2265-71. doi: 10.1128/JVI.72.3.2265-2271.1998. J Virol. 1998. PMID: 9499085 Free PMC article.

5

Processing of the MHV-A59 gene 1 polyprotein by the 3C-like proteinase.

Denison MR, Sims AC, Gibson CA, Lu XT. Denison MR, et al. Adv Exp Med Biol. 1998;440:121-7. doi: 10.1007/978-1-4615-5331-1_16. Adv Exp Med Biol. 1998. PMID: 9782273

6

Expression, purification, and activity of recombinant MHV-A59 3CLpro.

Sims AC, Lu XT, Denison MR. Sims AC, et al. Among authors: denison mr. Adv Exp Med Biol. 1998;440:129-34. doi: 10.1007/978-1-4615-5331-1_17. Adv Exp Med Biol. 1998. PMID: 9782274

7

The putative helicase of the coronavirus mouse hepatitis virus is processed from the replicase gene polyprotein and localizes in complexes that are active in viral RNA synthesis.

Denison MR, Spaan WJ, van der Meer Y, Gibson CA, Sims AC, Prentice E, Lu XT. Denison MR, et al. J Virol. 1999 Aug;73(8):6862-71. doi: 10.1128/JVI.73.8.6862-6871.1999. J Virol. 1999. PMID: 10400784 Free PMC article.

8

Four proteins processed from the replicase gene polyprotein of mouse hepatitis virus colocalize in the cell periphery and adjacent to sites of virion assembly.

Bost AG, Carnahan RH, Lu XT, Denison MR. Bost AG, et al. Among authors: denison mr. J Virol. 2000 Apr;74(7):3379-87. doi: 10.1128/jvi.74.7.3379-3387.2000. J Virol. 2000. PMID: 10708455 Free PMC article.

9

Mouse hepatitis virus replicase proteins associate with two distinct populations of intracellular membranes.

Sims AC, Ostermann J, Denison MR. Sims AC, et al. Among authors: denison mr. J Virol. 2000 Jun;74(12):5647-54. doi: 10.1128/jvi.74.12.5647-5654.2000. J Virol. 2000. PMID: 10823872 Free PMC article.

10

MHV-A59 gene 1 proteins are associated with two distinct membrane populations.

Denison MR, Sims AC. Denison MR, et al. Adv Exp Med Biol. 2001;494:655-61. doi: 10.1007/978-1-4615-1325-4_97. Adv Exp Med Biol. 2001. PMID: 11774541 No abstract available.

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