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An affinity-enhanced, broadly neutralizing heavy chain-only antibody protects against SARS-CoV-2 infection in animal models.
Schepens B, van Schie L, Nerinckx W, Roose K, Van Breedam W, Fijalkowska D, Devos S, Weyts W, De Cae S, Vanmarcke S, Lonigro C, Eeckhaut H, Van Herpe D, Borloo J, Oliveira AF, Catani JPP, Creytens S, De Vlieger D, Michielsen G, Marchan JCZ, Moschonas GD, Rossey I, Sedeyn K, Van Hecke A, Zhang X, Langendries L, Jacobs S, Ter Horst S, Seldeslachts L, Liesenborghs L, Boudewijns R, Thibaut HJ, Dallmeier K, Velde GV, Weynand B, Beer J, Schnepf D, Ohnemus A, Remory I, Foo CS, Abdelnabi R, Maes P, Kaptein SJF, Rocha-Pereira J, Jochmans D, Delang L, Peelman F, Staeheli P, Schwemmle M, Devoogdt N, Tersago D, Germani M, Heads J, Henry A, Popplewell A, Ellis M, Brady K, Turner A, Dombrecht B, Stortelers C, Neyts J, Callewaert N, Saelens X. Schepens B, et al. Among authors: devos s. Sci Transl Med. 2021 Nov 24;13(621):eabi7826. doi: 10.1126/scitranslmed.abi7826. Epub 2021 Nov 24. Sci Transl Med. 2021. PMID: 34609205 Free PMC article.
Yeast-produced fructosamine-3-kinase retains mobility after ex vivo intravitreal injection in human and bovine eyes as determined by Fluorescence Correlation Spectroscopy.
Minnaert AK, van Schie L, Grootaert H, Himpe J, Devos S, Weyts W, De Keersmaecker H, Braeckmans K, Van Aken E, Delanghe JR, De Smedt SC, Callewaert N, Remaut K. Minnaert AK, et al. Among authors: devos s. Int J Pharm. 2022 Jun 10;621:121772. doi: 10.1016/j.ijpharm.2022.121772. Epub 2022 Apr 26. Int J Pharm. 2022. PMID: 35487399
GlycoVHH: optimal sites for introducing N-glycans on the camelid VHH antibody scaffold and use for macrophage delivery.
van Schie L, Van Breedam W, Roels C, Schepens B, Frank M, Mehdipour AR, Laukens B, Nerinckx W, Santens F, Devos S, Rossey I, Thooft K, Vanmarcke S, Van Hecke A, Saelens X, Callewaert N. van Schie L, et al. Among authors: devos s. MAbs. 2023 Jan-Dec;15(1):2210709. doi: 10.1080/19420862.2023.2210709. MAbs. 2023. PMID: 37211816 Free PMC article.
GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins.
Meuris L, Santens F, Elson G, Festjens N, Boone M, Dos Santos A, Devos S, Rousseau F, Plets E, Houthuys E, Malinge P, Magistrelli G, Cons L, Chatel L, Devreese B, Callewaert N. Meuris L, et al. Among authors: devos s. Nat Biotechnol. 2014 May;32(5):485-9. doi: 10.1038/nbt.2885. Epub 2014 Apr 20. Nat Biotechnol. 2014. PMID: 24752077 Free PMC article.
119 results