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Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function.
Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, Johnston J, Madden K, Xu W, West J, Schrader S, Burkhead S, Heipel M, Brandt C, Kuijper JL, Kramer J, Conklin D, Presnell SR, Berry J, Shiota F, Bort S, Hambly K, Mudri S, Clegg C, Moore M, Grant FJ, Lofton-Day C, Gilbert T, Rayond F, Ching A, Yao L, Smith D, Webster P, Whitmore T, Maurer M, Kaushansky K, Holly RD, Foster D. Parrish-Novak J, et al. Among authors: dillon sr. Nature. 2000 Nov 2;408(6808):57-63. doi: 10.1038/35040504. Nature. 2000. PMID: 11081504
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease.
Gross JA, Johnston J, Mudri S, Enselman R, Dillon SR, Madden K, Xu W, Parrish-Novak J, Foster D, Lofton-Day C, Moore M, Littau A, Grossman A, Haugen H, Foley K, Blumberg H, Harrison K, Kindsvogel W, Clegg CH. Gross JA, et al. Among authors: dillon sr. Nature. 2000 Apr 27;404(6781):995-9. doi: 10.1038/35010115. Nature. 2000. PMID: 10801128
A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist.
Xu W, Presnell SR, Parrish-Novak J, Kindsvogel W, Jaspers S, Chen Z, Dillon SR, Gao Z, Gilbert T, Madden K, Schlutsmeyer S, Yao L, Whitmore TE, Chandrasekher Y, Grant FJ, Maurer M, Jelinek L, Storey H, Brender T, Hammond A, Topouzis S, Clegg CH, Foster DC. Xu W, et al. Among authors: dillon sr. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9511-6. doi: 10.1073/pnas.171303198. Epub 2001 Jul 31. Proc Natl Acad Sci U S A. 2001. PMID: 11481447 Free PMC article.
TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS.
Gross JA, Dillon SR, Mudri S, Johnston J, Littau A, Roque R, Rixon M, Schou O, Foley KP, Haugen H, McMillen S, Waggie K, Schreckhise RW, Shoemaker K, Vu T, Moore M, Grossman A, Clegg CH. Gross JA, et al. Among authors: dillon sr. Immunity. 2001 Aug;15(2):289-302. doi: 10.1016/s1074-7613(01)00183-2. Immunity. 2001. PMID: 11520463 Free article.
Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice.
Dillon SR, Sprecher C, Hammond A, Bilsborough J, Rosenfeld-Franklin M, Presnell SR, Haugen HS, Maurer M, Harder B, Johnston J, Bort S, Mudri S, Kuijper JL, Bukowski T, Shea P, Dong DL, Dasovich M, Grant FJ, Lockwood L, Levin SD, LeCiel C, Waggie K, Day H, Topouzis S, Kramer J, Kuestner R, Chen Z, Foster D, Parrish-Novak J, Gross JA. Dillon SR, et al. Nat Immunol. 2004 Jul;5(7):752-60. doi: 10.1038/ni1084. Epub 2004 Jun 6. Nat Immunol. 2004. PMID: 15184896
B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin.
Dillon SR, Harder B, Lewis KB, Moore MD, Liu H, Bukowski TR, Hamacher NB, Lantry MM, Maurer M, Krejsa CM, Ellsworth JL, Pederson S, Elkon KB, Wener MH, Dall'Era M, Gross JA. Dillon SR, et al. Arthritis Res Ther. 2010;12(2):R48. doi: 10.1186/ar2959. Epub 2010 Mar 19. Arthritis Res Ther. 2010. PMID: 20302641 Free PMC article.
68 results