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Bisoprolol and fluvastatin for the reduction of perioperative cardiac mortality and myocardial infarction in intermediate-risk patients undergoing noncardiovascular surgery: a randomized controlled trial (DECREASE-IV).
Dunkelgrun M, Boersma E, Schouten O, Koopman-van Gemert AW, van Poorten F, Bax JJ, Thomson IR, Poldermans D; Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. Dunkelgrun M, et al. Ann Surg. 2009 Jun;249(6):921-6. doi: 10.1097/SLA.0b013e3181a77d00. Ann Surg. 2009. PMID: 19474688 Clinical Trial.
Bisoprolol reduces cardiac death and myocardial infarction in high-risk patients as long as 2 years after successful major vascular surgery.
Poldermans D, Boersma E, Bax JJ, Thomson IR, Paelinck B, van de Ven LL, Scheffer MG, Trocino G, Vigna C, Baars HF, van Urk H, Roelandt JR; Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. Poldermans D, et al. Eur Heart J. 2001 Aug;22(15):1353-8. doi: 10.1053/euhj.2000.2555. Eur Heart J. 2001. PMID: 11465968 Clinical Trial.
Fluvastatin and perioperative events in patients undergoing vascular surgery.
Schouten O, Boersma E, Hoeks SE, Benner R, van Urk H, van Sambeek MR, Verhagen HJ, Khan NA, Dunkelgrun M, Bax JJ, Poldermans D; Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group. Schouten O, et al. N Engl J Med. 2009 Sep 3;361(10):980-9. doi: 10.1056/NEJMoa0808207. N Engl J Med. 2009. PMID: 19726772 Free article. Clinical Trial.