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Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection.
Townsend L, Dyer AH, Jones K, Dunne J, Mooney A, Gaffney F, O'Connor L, Leavy D, O'Brien K, Dowds J, Sugrue JA, Hopkins D, Martin-Loeches I, Ni Cheallaigh C, Nadarajan P, McLaughlin AM, Bourke NM, Bergin C, O'Farrelly C, Bannan C, Conlon N. Townsend L, et al. Among authors: dyer ah. PLoS One. 2020 Nov 9;15(11):e0240784. doi: 10.1371/journal.pone.0240784. eCollection 2020. PLoS One. 2020. PMID: 33166287 Free PMC article.
Persistent Poor Health after COVID-19 Is Not Associated with Respiratory Complications or Initial Disease Severity.
Townsend L, Dowds J, O'Brien K, Sheill G, Dyer AH, O'Kelly B, Hynes JP, Mooney A, Dunne J, Ni Cheallaigh C, O'Farrelly C, Bourke NM, Conlon N, Martin-Loeches I, Bergin C, Nadarajan P, Bannan C. Townsend L, et al. Among authors: dyer ah. Ann Am Thorac Soc. 2021 Jun;18(6):997-1003. doi: 10.1513/AnnalsATS.202009-1175OC. Ann Am Thorac Soc. 2021. PMID: 33413026 Free PMC article.
Prolonged elevation of D-dimer levels in convalescent COVID-19 patients is independent of the acute phase response.
Townsend L, Fogarty H, Dyer A, Martin-Loeches I, Bannan C, Nadarajan P, Bergin C, O'Farrelly C, Conlon N, Bourke NM, Ward SE, Byrne M, Ryan K, O'Connell N, O'Sullivan JM, Ni Cheallaigh C, O'Donnell JS. Townsend L, et al. J Thromb Haemost. 2021 Apr;19(4):1064-1070. doi: 10.1111/jth.15267. Epub 2021 Mar 8. J Thromb Haemost. 2021. PMID: 33587810 Free PMC article.
Longitudinal Analysis of COVID-19 Patients Shows Age-Associated T Cell Changes Independent of Ongoing Ill-Health.
Townsend L, Dyer AH, Naughton A, Kiersey R, Holden D, Gardiner M, Dowds J, O'Brien K, Bannan C, Nadarajan P, Dunne J, Martin-Loeches I, Fallon PG, Bergin C, O'Farrelly C, Cheallaigh CN, Bourke NM, Conlon N. Townsend L, et al. Among authors: dyer ah. Front Immunol. 2021 May 7;12:676932. doi: 10.3389/fimmu.2021.676932. eCollection 2021. Front Immunol. 2021. PMID: 34025675 Free PMC article.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Among authors: dyer ah. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
Previous SARS-CoV-2 Infection, Age, and Frailty Are Associated With 6-Month Vaccine-Induced Anti-Spike Antibody Titer in Nursing Home Residents.
Dyer AH, Noonan C, McElheron M, Batten I, Reddy C, Connolly E, Pierpoint R, Murray C, Leonard A, Higgins C, Reilly P, Boran G, Phelan T, McCormack W, O'Neill D, Fallon A, Brady G, O'Farrelly C, Bourke NM, Kennelly SP. Dyer AH, et al. J Am Med Dir Assoc. 2022 Mar;23(3):434-439. doi: 10.1016/j.jamda.2021.12.001. Epub 2022 Jan 11. J Am Med Dir Assoc. 2022. PMID: 35219507 Free PMC article.
Severe COVID-19 is characterised by inflammation and immature myeloid cells early in disease progression.
Townsend L, Dyer AH, Naughton A, Imangaliyev S, Dunne J, Kiersey R, Holden D, Mooney A, Leavy D, Ridge K, Sugrue J, Aldoseri M, Kelliher JH, Hennessy M, Byrne D, Browne P, Bacon CL, Doyle C, O'Riordan R, McLaughlin AM, Bannan C, Martin-Loeches I, White A, McLoughlin RM, Bergin C, Bourke NM, O'Farrelly C, Conlon N, Cheallaigh CN; STAR COVID Bioresource. Townsend L, et al. Among authors: dyer ah. Heliyon. 2022 Apr;8(4):e09230. doi: 10.1016/j.heliyon.2022.e09230. Epub 2022 Apr 1. Heliyon. 2022. PMID: 35386227 Free PMC article.
66 results