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CCN2 is necessary for the function of mouse embryonic fibroblasts.
Kennedy L, Liu S, Shi-Wen X, Chen Y, Eastwood M, Sabetkar M, Carter DE, Lyons KM, Black CM, Abraham DJ, Leask A. Kennedy L, et al. Among authors: eastwood m. Exp Cell Res. 2007 Mar 10;313(5):952-64. doi: 10.1016/j.yexcr.2006.12.006. Epub 2006 Dec 23. Exp Cell Res. 2007. PMID: 17239853
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.
Shi-Wen X, Chen Y, Denton CP, Eastwood M, Renzoni EA, Bou-Gharios G, Pearson JD, Dashwood M, du Bois RM, Black CM, Leask A, Abraham DJ. Shi-Wen X, et al. Among authors: eastwood m. Mol Biol Cell. 2004 Jun;15(6):2707-19. doi: 10.1091/mbc.e03-12-0902. Epub 2004 Mar 26. Mol Biol Cell. 2004. PMID: 15047866 Free PMC article.
Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts.
Chen Y, Leask A, Abraham DJ, Pala D, Shiwen X, Khan K, Liu S, Carter DE, Wilcox-Adelman S, Goetinck P, Denton CP, Black CM, Pitsillides AA, Sarraf CE, Eastwood M. Chen Y, et al. Among authors: eastwood m. Arthritis Rheum. 2008 Feb;58(2):577-85. doi: 10.1002/art.23146. Arthritis Rheum. 2008. PMID: 18240216 Free article.
Requirement of transforming growth factor beta-activated kinase 1 for transforming growth factor beta-induced alpha-smooth muscle actin expression and extracellular matrix contraction in fibroblasts.
Shi-wen X, Parapuram SK, Pala D, Chen Y, Carter DE, Eastwood M, Denton CP, Abraham DJ, Leask A. Shi-wen X, et al. Among authors: eastwood m. Arthritis Rheum. 2009 Jan;60(1):234-41. doi: 10.1002/art.24223. Arthritis Rheum. 2009. PMID: 19116914 Free article.
415 results