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Page 1
Showing results for ester za
Search for Esther ZA instead (1 results)
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.
van der Kant R, Langness VF, Herrera CM, Williams DA, Fong LK, Leestemaker Y, Steenvoorden E, Rynearson KD, Brouwers JF, Helms JB, Ovaa H, Giera M, Wagner SL, Bang AG, Goldstein LSB. van der Kant R, et al. Cell Stem Cell. 2019 Mar 7;24(3):363-375.e9. doi: 10.1016/j.stem.2018.12.013. Epub 2019 Jan 24. Cell Stem Cell. 2019. PMID: 30686764 Free PMC article.
Here, we perform a phenotypic screen for pTau accumulation in AD-patient iPSC-derived neurons and identify cholesteryl esters (CE), the storage product of excess cholesterol, as upstream regulators of Tau early during AD development. ...
Here, we perform a phenotypic screen for pTau accumulation in AD-patient iPSC-derived neurons and identify cholesteryl esters (CE), t …
1,4-Dihydropyridinebutyrolactone-derived ring-opened ester and amide analogs targeting BET bromodomains.
Jiang J, Zhao PL, Sigua LH, Chan A, Schönbrunn E, Qi J, Georg GI. Jiang J, et al. Arch Pharm (Weinheim). 2022 Nov;355(11):e2200288. doi: 10.1002/ardp.202200288. Epub 2022 Aug 8. Arch Pharm (Weinheim). 2022. PMID: 35941525 Free PMC article.
Based on a previously reported 1,4-dihydropyridinebutyrolactone virtual screening hit, nine lactone ring-opened ester and seven amide analogs were prepared. The analogs were designed to provide interactions with residues at the entrance of the ZA loop of the testis- …
Based on a previously reported 1,4-dihydropyridinebutyrolactone virtual screening hit, nine lactone ring-opened ester and seven amide …
Uremic Toxins and Vascular Dysfunction.
Six I, Flissi N, Lenglet G, Louvet L, Kamel S, Gallet M, Massy ZA, Liabeuf S. Six I, et al. Toxins (Basel). 2020 Jun 18;12(6):404. doi: 10.3390/toxins12060404. Toxins (Basel). 2020. PMID: 32570781 Free PMC article. Review.
The Chemistry behind Chocolate Production.
Barišić V, Kopjar M, Jozinović A, Flanjak I, Ačkar Đ, Miličević B, Šubarić D, Jokić S, Babić J. Barišić V, et al. Molecules. 2019 Aug 30;24(17):3163. doi: 10.3390/molecules24173163. Molecules. 2019. PMID: 31480281 Free PMC article. Review.
Additionally, we present other components that may be naturally present or form during the production process, such as methylxanthines, aldehydes, esters, ketones, pyrazines, acids, and alcohols....
Additionally, we present other components that may be naturally present or form during the production process, such as methylxanthines, alde …
[Research progress on rutin derivatives].
Mao YJ, Feng YL, Wang MJ, Lyu ZY, Zhai GY. Mao YJ, et al. Zhongguo Zhong Yao Za Zhi. 2021 Sep;46(18):4654-4665. doi: 10.19540/j.cnki.cjcmm.20210429.602. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34581073 Review. Chinese.
In view of this, its structure is optimized and modified to afford rutin derivatives with good solubility, high bioavailability, stable metabolism and small toxic side effects. So far, a large number of rutin ethers, esters, and complexes have been synthesized and undergon …
In view of this, its structure is optimized and modified to afford rutin derivatives with good solubility, high bioavailability, stable meta …
[Research progress on Polygalae Radix].
Liu L, Feng WH, Liu XQ, Liang YH, Li C, Wang ZM. Liu L, et al. Zhongguo Zhong Yao Za Zhi. 2021 Nov;46(22):5744-5759. doi: 10.19540/j.cnki.cjcmm.20210518.601. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34951162 Review. Chinese.
Modern research has revealed that Polygalae Radix mainly contains triterpenoid saponins, xanthone, oligosaccharide esters, etc., with the activities of improving memory, resisting dementia, protecting the brain, relieving cough, and removing phlegm, as well as sedation and …
Modern research has revealed that Polygalae Radix mainly contains triterpenoid saponins, xanthone, oligosaccharide esters, etc., with …
[Research progress in tigliane-type macrocyclic diterpenoids].
Tan HH, Xia M, Su P, Huang LQ. Tan HH, et al. Zhongguo Zhong Yao Za Zhi. 2023 Sep;48(17):4620-4633. doi: 10.19540/j.cnki.cjcmm.20230427.201. Zhongguo Zhong Yao Za Zhi. 2023. PMID: 37802801 Review. Chinese.
According to the different functional groups, they can be classified into types of phorbol esters, C-4 deoxyphorbol esters, C-12 deoxyphorbol esters, C-16 or C-17 substituted phorbol esters and others. ...
According to the different functional groups, they can be classified into types of phorbol esters, C-4 deoxyphorbol esters, C- …
[A new monoterpene ester from Zingiberis Rhizoma Recens].
Zhang XJ, Song ZM, Wang YZ, Wang YF, Cai YJ, Hu XY, Feng WS. Zhang XJ, et al. Zhongguo Zhong Yao Za Zhi. 2021 Oct;46(19):5015-5019. doi: 10.19540/j.cnki.cjcmm.20210705.202. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34738396 Chinese.
The five compounds were identified as(2E,6Z)-8-hydroxy-2,6-dimethylocta-2,6-dien-1-yl-(E)-3-(4-hydroxy-3-methoxyphenyl) acrylate(1),(2E,6E)-8-hydroxy-3,7-dimethylocta-2,6-die-noic acid(2),(E)-1,8-dihydroxy-3,7-dimethyl-2-octenoic acid(3), linalyl-beta-D-glucopyranoside(4), and be …
The five compounds were identified as(2E,6Z)-8-hydroxy-2,6-dimethylocta-2,6-dien-1-yl-(E)-3-(4-hydroxy-3-methoxyphenyl) acrylate(1),(2E,6E)- …
An antifouling model from the sea: a review of 25 years of zosteric acid studies.
Vilas-Boas C, Sousa E, Pinto M, Correia-da-Silva M. Vilas-Boas C, et al. Biofouling. 2017 Nov;33(10):927-942. doi: 10.1080/08927014.2017.1391951. Epub 2017 Nov 24. Biofouling. 2017. PMID: 29171304 Review.
ZA was shown to have appropriate environmental fate parameters such as high water solubility, a low log P, low bioaccumulation, and no ecotoxicity, which demonstrated the potential of ZA as a safe AF agent. ...The synthesis of analogs is also considered in this revi …
ZA was shown to have appropriate environmental fate parameters such as high water solubility, a low log P, low bioaccumulation, and n …
[A new cinnamic acid ester derivative from Liquidambaris Resina].
Xu SY, Xiao QW, Zhao SM, Guan YJ, Yuan LH, Zhu Y, Wang CJ, Yan PC, Dong JY. Xu SY, et al. Zhongguo Zhong Yao Za Zhi. 2023 Aug;48(15):4130-4136. doi: 10.19540/j.cnki.cjcmm.20230426.201. Zhongguo Zhong Yao Za Zhi. 2023. PMID: 37802781 Chinese.
Their structures were identified on the basis of spectral data, electron capture detector data, and physicochemical properties as(2'R, 3'R)-2',3'-dihydroxy-hydrocinnamyl-(E)-cinnamate(1),(E)-cinnamyl-(E)-cinnamate(2), cinnamic acid(3), 28-norlup-20(29)-en-3-one-17beta-hydroperoxi …
Their structures were identified on the basis of spectral data, electron capture detector data, and physicochemical properties as(2'R, 3'R)- …
869 results