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Intestinal TGR5 agonism improves hepatic steatosis and insulin sensitivity in Western diet-fed mice.
Finn PD, Rodriguez D, Kohler J, Jiang Z, Wan S, Blanco E, King AJ, Chen T, Bell N, Dragoli D, Jacobs JW, Jain R, Leadbetter M, Siegel M, Carreras CW, Koo-McCoy S, Shaw K, Le C, Vanegas S, Hsu IH, Kozuka K, Okamoto K, Caldwell JS, Lewis JG. Finn PD, et al. Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G412-G424. doi: 10.1152/ajpgi.00300.2018. Epub 2019 Jan 3. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30605011 Free PMC article.
A Potent and Selective AMPK Activator That Inhibits de Novo Lipogenesis.
Gómez-Galeno JE, Dang Q, Nguyen TH, Boyer SH, Grote MP, Sun Z, Chen M, Craigo WA, van Poelje PD, MacKenna DA, Cable EE, Rolzin PA, Finn PD, Chi B, Linemeyer DL, Hecker SJ, Erion MD. Gómez-Galeno JE, et al. Among authors: finn pd. ACS Med Chem Lett. 2010 Aug 30;1(9):478-82. doi: 10.1021/ml100143q. eCollection 2010 Dec 9. ACS Med Chem Lett. 2010. PMID: 24900234 Free PMC article.
Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index.
Erion MD, Cable EE, Ito BR, Jiang H, Fujitaki JM, Finn PD, Zhang BH, Hou J, Boyer SH, van Poelje PD, Linemeyer DL. Erion MD, et al. Among authors: finn pd. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15490-5. doi: 10.1073/pnas.0702759104. Epub 2007 Sep 18. Proc Natl Acad Sci U S A. 2007. PMID: 17878314 Free PMC article.
Serotonergic neurons are targets for leptin in the monkey.
Finn PD, Cunningham MJ, Rickard DG, Clifton DK, Steiner RA. Finn PD, et al. J Clin Endocrinol Metab. 2001 Jan;86(1):422-6. doi: 10.1210/jcem.86.1.7128. J Clin Endocrinol Metab. 2001. PMID: 11232034
19 results