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Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase.
Eur J Med Chem. 2019 Jan 15;162:455-464. doi: 10.1016/j.ejmech.2018.11.010. Epub 2018 Nov 14.
Eur J Med Chem. 2019.
PMID: 30469041
Free PMC article.
O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1.
Malachowski WP, Winters M, DuHadaway JB, Lewis-Ballester A, Badir S, Wai J, Rahman M, Sheikh E, LaLonde JM, Yeh SR, Prendergast GC, Muller AJ.
Malachowski WP, et al.
Eur J Med Chem. 2016 Jan 27;108:564-576. doi: 10.1016/j.ejmech.2015.12.028. Epub 2015 Dec 17.
Eur J Med Chem. 2016.
PMID: 26717206
Free PMC article.
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The enantioselective construction of tetracyclic diterpene skeletons with Friedel-Crafts alkylation and palladium-catalyzed cycloalkenylation reactions.
Burke SJ, Malachowski WP, Mehta SK, Appenteng R.
Burke SJ, et al.
Org Biomol Chem. 2015 Mar 7;13(9):2726-44. doi: 10.1039/c4ob02489c.
Org Biomol Chem. 2015.
PMID: 25598198
Free PMC article.
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Enantioselective synthesis of decalin structures with all-carbon quaternary centers via one-pot sequential Cope/Rauhut-Currier reaction.
Ross TM, Burke S, Malachowski WP.
Ross TM, et al.
Tetrahedron Lett. 2014 Aug 13;55(33):4616-4618. doi: 10.1016/j.tetlet.2014.06.085.
Tetrahedron Lett. 2014.
PMID: 25125710
Free PMC article.
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