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Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients.
Pierce CA, Preston-Hurlburt P, Dai Y, Aschner CB, Cheshenko N, Galen B, Garforth SJ, Herrera NG, Jangra RK, Morano NC, Orner E, Sy S, Chandran K, Dziura J, Almo SC, Ring A, Keller MJ, Herold KC, Herold BC. Pierce CA, et al. Among authors: garforth sj. Sci Transl Med. 2020 Oct 7;12(564):eabd5487. doi: 10.1126/scitranslmed.abd5487. Epub 2020 Sep 21. Sci Transl Med. 2020. PMID: 32958614 Free PMC article.
PD-L1 is an activation-independent marker of brown adipocytes.
Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL. Ingram JR, et al. Nat Commun. 2017 Sep 21;8(1):647. doi: 10.1038/s41467-017-00799-8. Nat Commun. 2017. PMID: 28935898 Free PMC article.
Anti-CTLA-4 therapy requires an Fc domain for efficacy.
Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, Dougan SK, Ploegh HL, Dougan M. Ingram JR, et al. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):3912-3917. doi: 10.1073/pnas.1801524115. Epub 2018 Mar 26. Proc Natl Acad Sci U S A. 2018. PMID: 29581255 Free PMC article.
A naturally occurring antiviral ribonucleotide encoded by the human genome.
Gizzi AS, Grove TL, Arnold JJ, Jose J, Jangra RK, Garforth SJ, Du Q, Cahill SM, Dulyaninova NG, Love JD, Chandran K, Bresnick AR, Cameron CE, Almo SC. Gizzi AS, et al. Among authors: garforth sj. Nature. 2018 Jun;558(7711):610-614. doi: 10.1038/s41586-018-0238-4. Epub 2018 Jun 20. Nature. 2018. PMID: 29925952 Free PMC article.
Structural Basis of CD160:HVEM Recognition.
Liu W, Garrett SC, Fedorov EV, Ramagopal UA, Garforth SJ, Bonanno JB, Almo SC. Liu W, et al. Among authors: garforth sj. Structure. 2019 Aug 6;27(8):1286-1295.e4. doi: 10.1016/j.str.2019.05.010. Epub 2019 Jun 20. Structure. 2019. PMID: 31230945 Free PMC article.
Mechanistic dissection of the PD-L1:B7-1 co-inhibitory immune complex.
Garrett-Thomson SC, Massimi A, Fedorov EV, Bonanno JB, Scandiuzzi L, Hillerich B, Seidel RD 3rd, Love JD, Garforth SJ, Guha C, Almo SC. Garrett-Thomson SC, et al. Among authors: garforth sj. PLoS One. 2020 Jun 4;15(6):e0233578. doi: 10.1371/journal.pone.0233578. eCollection 2020. PLoS One. 2020. PMID: 32497097 Free PMC article.
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