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Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Bethune MT, Gee MH, Bunse M, Lee MS, Gschweng EH, Pagadala MS, Zhou J, Cheng D, Heath JR, Kohn DB, Kuhns MS, Uckert W, Baltimore D. Bethune MT, et al. Among authors: gee mh. Elife. 2016 Nov 8;5:e19095. doi: 10.7554/eLife.19095. Elife. 2016. PMID: 27823582 Free PMC article.
Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
Sibener LV, Fernandes RA, Kolawole EM, Carbone CB, Liu F, McAffee D, Birnbaum ME, Yang X, Su LF, Yu W, Dong S, Gee MH, Jude KM, Davis MM, Groves JT, Goddard WA 3rd, Heath JR, Evavold BD, Vale RD, Garcia KC. Sibener LV, et al. Among authors: gee mh. Cell. 2018 Jul 26;174(3):672-687.e27. doi: 10.1016/j.cell.2018.06.017. Cell. 2018. PMID: 30053426 Free PMC article.
Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes.
Gee MH, Han A, Lofgren SM, Beausang JF, Mendoza JL, Birnbaum ME, Bethune MT, Fischer S, Yang X, Gomez-Eerland R, Bingham DB, Sibener LV, Fernandes RA, Velasco A, Baltimore D, Schumacher TN, Khatri P, Quake SR, Davis MM, Garcia KC. Gee MH, et al. Cell. 2018 Jan 25;172(3):549-563.e16. doi: 10.1016/j.cell.2017.11.043. Epub 2017 Dec 21. Cell. 2018. PMID: 29275860 Free PMC article.
Tuning T cell receptor sensitivity through catch bond engineering.
Zhao X, Kolawole EM, Chan W, Feng Y, Yang X, Gee MH, Jude KM, Sibener LV, Fordyce PM, Germain RN, Evavold BD, Garcia KC. Zhao X, et al. Among authors: gee mh. Science. 2022 Apr 8;376(6589):eabl5282. doi: 10.1126/science.abl5282. Epub 2022 Apr 8. Science. 2022. PMID: 35389803 Free PMC article.
T cell receptor cross-reactivity expanded by dramatic peptide-MHC adaptability.
Riley TP, Hellman LM, Gee MH, Mendoza JL, Alonso JA, Foley KC, Nishimura MI, Vander Kooi CW, Garcia KC, Baker BM. Riley TP, et al. Among authors: gee mh. Nat Chem Biol. 2018 Oct;14(10):934-942. doi: 10.1038/s41589-018-0130-4. Epub 2018 Sep 17. Nat Chem Biol. 2018. PMID: 30224695 Free PMC article.
633 results