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An expanded peripheral T cell population to a cytotoxic T lymphocyte (CTL)-defined, melanocyte-specific antigen in metastatic melanoma patients impacts on generation of peptide-specific CTLs but does not overcome tumor escape from immune surveillance in metastatic lesions.
Anichini A, Molla A, Mortarini R, Tragni G, Bersani I, Di Nicola M, Gianni AM, Pilotti S, Dunbar R, Cerundolo V, Parmiani G. Anichini A, et al. Among authors: gianni am. J Exp Med. 1999 Sep 6;190(5):651-67. doi: 10.1084/jem.190.5.651. J Exp Med. 1999. PMID: 10477550 Free PMC article.
Autologous dendritic cells derived from CD34+ progenitors and from monocytes are not functionally equivalent antigen-presenting cells in the induction of melan-A/Mart-1(27-35)-specific CTLs from peripheral blood lymphocytes of melanoma patients with low frequency of CTL precursors.
Mortarini R, Anichini A, Di Nicola M, Siena S, Bregni M, Belli F, Molla A, Gianni AM, Parmiani G. Mortarini R, et al. Among authors: gianni am. Cancer Res. 1997 Dec 15;57(24):5534-41. Cancer Res. 1997. PMID: 9407964
323 results