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Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination.
Loyal L, Braun J, Henze L, Kruse B, Dingeldey M, Reimer U, Kern F, Schwarz T, Mangold M, Unger C, Dörfler F, Kadler S, Rosowski J, Gürcan K, Uyar-Aydin Z, Frentsch M, Kurth F, Schnatbaum K, Eckey M, Hippenstiel S, Hocke A, Müller MA, Sawitzki B, Miltenyi S, Paul F, Mall MA, Wenschuh H, Voigt S, Drosten C, Lauster R, Lachman N, Sander LE, Corman VM, Röhmel J, Meyer-Arndt L, Thiel A, Giesecke-Thiel C. Loyal L, et al. Among authors: giesecke thiel c. Science. 2021 Oct 8;374(6564):eabh1823. doi: 10.1126/science.abh1823. Epub 2021 Oct 8. Science. 2021. PMID: 34465633 Free PMC article.
SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19.
Braun J, Loyal L, Frentsch M, Wendisch D, Georg P, Kurth F, Hippenstiel S, Dingeldey M, Kruse B, Fauchere F, Baysal E, Mangold M, Henze L, Lauster R, Mall MA, Beyer K, Röhmel J, Voigt S, Schmitz J, Miltenyi S, Demuth I, Müller MA, Hocke A, Witzenrath M, Suttorp N, Kern F, Reimer U, Wenschuh H, Drosten C, Corman VM, Giesecke-Thiel C, Sander LE, Thiel A. Braun J, et al. Nature. 2020 Nov;587(7833):270-274. doi: 10.1038/s41586-020-2598-9. Epub 2020 Jul 29. Nature. 2020. PMID: 32726801
Cutting Edge: Serum but Not Mucosal Antibody Responses Are Associated with Pre-Existing SARS-CoV-2 Spike Cross-Reactive CD4+ T Cells following BNT162b2 Vaccination in the Elderly.
Meyer-Arndt L, Schwarz T, Loyal L, Henze L, Kruse B, Dingeldey M, Gürcan K, Uyar-Aydin Z, Müller MA, Drosten C, Paul F, Sander LE, Demuth I, Lauster R, Giesecke-Thiel C, Braun J, Corman VM, Thiel A. Meyer-Arndt L, et al. Among authors: giesecke thiel c. J Immunol. 2022 Mar 1;208(5):1001-1005. doi: 10.4049/jimmunol.2100990. Epub 2022 Feb 4. J Immunol. 2022. PMID: 35121642
SARS-CoV-2 mRNA vaccinations fail to elicit humoral and cellular immune responses in patients with multiple sclerosis receiving fingolimod.
Meyer-Arndt L, Braun J, Fauchere F, Vanshylla K, Loyal L, Henze L, Kruse B, Dingeldey M, Jürchott K, Mangold M, Maraj A, Braginets A, Böttcher C, Nitsche A, de la Rosa K, Ratswohl C, Sawitzki B, Holenya P, Reimer U, Sander LE, Klein F, Paul F, Bellmann-Strobl J, Thiel A, Giesecke-Thiel C. Meyer-Arndt L, et al. Among authors: giesecke thiel c. J Neurol Neurosurg Psychiatry. 2022 Sep;93(9):960-971. doi: 10.1136/jnnp-2022-329395. Epub 2022 Jul 14. J Neurol Neurosurg Psychiatry. 2022. PMID: 35835468 Free PMC article.
Generation of HBsAg-reactive T- and B-cells following HBV vaccination in serological non-responders under hemodialysis treatment.
Roch T, Giesecke-Thiel C, Blazquez-Navarro A, Wehler P, Thieme CJ, Juelke K, Grütz G, Hörstrup J, Witzke O, Dittmer U, Stervbo U, Reinke P, Westhoff TH, Babel N. Roch T, et al. Among authors: giesecke thiel c. Eur J Immunol. 2021 May;51(5):1278-1281. doi: 10.1002/eji.202048756. Epub 2021 Feb 9. Eur J Immunol. 2021. PMID: 33459347 Free article.
Dnmt1 has de novo activity targeted to transposable elements.
Haggerty C, Kretzmer H, Riemenschneider C, Kumar AS, Mattei AL, Bailly N, Gottfreund J, Giesselmann P, Weigert R, Brändl B, Giehr P, Buschow R, Galonska C, von Meyenn F, Pappalardi MB, McCabe MT, Wittler L, Giesecke-Thiel C, Mielke T, Meierhofer D, Timmermann B, Müller FJ, Walter J, Meissner A. Haggerty C, et al. Among authors: giesecke thiel c. Nat Struct Mol Biol. 2021 Jul;28(7):594-603. doi: 10.1038/s41594-021-00603-8. Epub 2021 Jun 17. Nat Struct Mol Biol. 2021. PMID: 34140676 Free PMC article.
16 results