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Aging immunity may exacerbate COVID-19.
Akbar AN, Gilroy DW. Akbar AN, et al. Among authors: gilroy dw. Science. 2020 Jul 17;369(6501):256-257. doi: 10.1126/science.abb0762. Science. 2020. PMID: 32675364 No abstract available.
Sestrins induce natural killer function in senescent-like CD8+ T cells.
Pereira BI, De Maeyer RPH, Covre LP, Nehar-Belaid D, Lanna A, Ward S, Marches R, Chambers ES, Gomes DCO, Riddell NE, Maini MK, Teixeira VH, Janes SM, Gilroy DW, Larbi A, Mabbott NA, Ucar D, Kuchel GA, Henson SM, Strid J, Lee JH, Banchereau J, Akbar AN. Pereira BI, et al. Among authors: gilroy dw. Nat Immunol. 2020 Jun;21(6):684-694. doi: 10.1038/s41590-020-0643-3. Epub 2020 Mar 30. Nat Immunol. 2020. PMID: 32231301 Free PMC article.
An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory.
Lanna A, Vaz B, D'Ambra C, Valvo S, Vuotto C, Chiurchiù V, Devine O, Sanchez M, Borsellino G, Akbar AN, De Bardi M, Gilroy DW, Dustin ML, Blumer B, Karin M. Lanna A, et al. Among authors: gilroy dw. Nat Cell Biol. 2022 Oct;24(10):1461-1474. doi: 10.1038/s41556-022-00991-z. Epub 2022 Sep 15. Nat Cell Biol. 2022. PMID: 36109671 Free PMC article.
Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS.
Pallett LJ, Swadling L, Diniz M, Maini AA, Schwabenland M, Gasull AD, Davies J, Kucykowicz S, Skelton JK, Thomas N, Schmidt NM, Amin OE, Gill US, Stegmann KA, Burton AR, Stephenson E, Reynolds G, Whelan M, Sanchez J, de Maeyer R, Thakker C, Suveizdyte K, Uddin I, Ortega-Prieto AM, Grant C, Froghi F, Fusai G, Lens S, Pérez-Del-Pulgar S, Al-Akkad W, Mazza G, Noursadeghi M, Akbar A, Kennedy PTF, Davidson BR, Prinz M, Chain BM, Haniffa M, Gilroy DW, Dorner M, Bengsch B, Schurich A, Maini MK. Pallett LJ, et al. Among authors: gilroy dw. Nature. 2023 Feb;614(7947):334-342. doi: 10.1038/s41586-022-05645-6. Epub 2023 Jan 25. Nature. 2023. PMID: 36697826
Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose.
Reynolds CJ, Pade C, Gibbons JM, Butler DK, Otter AD, Menacho K, Fontana M, Smit A, Sackville-West JE, Cutino-Moguel T, Maini MK, Chain B, Noursadeghi M; UK COVIDsortium Immune Correlates Network; Brooks T, Semper A, Manisty C, Treibel TA, Moon JC; UK COVIDsortium Investigators; Valdes AM, McKnight Á, Altmann DM, Boyton R. Reynolds CJ, et al. Science. 2021 Apr 30;372(6549):1418-23. doi: 10.1126/science.abh1282. Online ahead of print. Science. 2021. PMID: 33931567 Free PMC article.
125 results