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Page 1
Immunosuppressive drug azathioprine reduces aneurysm progression through inhibition of Rac1 and c-Jun-terminal-N-kinase in endothelial cells.
Marinkovic G, Hibender S, Hoogenboezem M, van Broekhoven A, Girigorie AF, Bleeker N, Hamers AA, Stap J, van Buul JD, de Vries CJ, de Waard V. Marinkovic G, et al. Among authors: girigorie af. Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2380-8. doi: 10.1161/ATVBAHA.113.301394. Epub 2013 Aug 15. Arterioscler Thromb Vasc Biol. 2013. PMID: 23950142
Terminal differentiation of T cells is strongly associated with CMV infection and increased in HIV-positive individuals on ART and lifestyle matched controls.
Booiman T, Wit FW, Girigorie AF, Maurer I, De Francesco D, Sabin CA, Harskamp AM, Prins M, Franceschi C, Deeks SG, Winston A, Reiss P, Kootstra NA; Co-morBidity in Relation to Aids (COBRA) Collaboration. Booiman T, et al. Among authors: girigorie af. PLoS One. 2017 Aug 14;12(8):e0183357. doi: 10.1371/journal.pone.0183357. eCollection 2017. PLoS One. 2017. PMID: 28806406 Free PMC article.
High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid.
Booiman T, Wit FW, Maurer I, De Francesco D, Sabin CA, Harskamp AM, Prins M, Garagnani P, Pirazzini C, Franceschi C, Fuchs D, Gisslén M, Winston A, Reiss P, Kootstra NA; Comorbidity in Relation to AIDS (COBRA) Collaboration. Booiman T, et al. Open Forum Infect Dis. 2017 May 25;4(3):ofx108. doi: 10.1093/ofid/ofx108. eCollection 2017 Summer. Open Forum Infect Dis. 2017. PMID: 28680905 Free PMC article.
Increased brain-predicted aging in treated HIV disease.
Cole JH, Underwood J, Caan MW, De Francesco D, van Zoest RA, Leech R, Wit FW, Portegies P, Geurtsen GJ, Schmand BA, Schim van der Loeff MF, Franceschi C, Sabin CA, Majoie CB, Winston A, Reiss P, Sharp DJ; COBRA collaboration. Cole JH, et al. Neurology. 2017 Apr 4;88(14):1349-1357. doi: 10.1212/WNL.0000000000003790. Epub 2017 Mar 3. Neurology. 2017. PMID: 28258081 Free PMC article.
Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers.
van Zoest RA, Underwood J, De Francesco D, Sabin CA, Cole JH, Wit FW, Caan MWA, Kootstra NA, Fuchs D, Zetterberg H, Majoie CBLM, Portegies P, Winston A, Sharp DJ, Gisslén M, Reiss P; Comorbidity in Relation to AIDS (COBRA) Collaboration. van Zoest RA, et al. J Infect Dis. 2017 Dec 27;217(1):69-81. doi: 10.1093/infdis/jix553. J Infect Dis. 2017. PMID: 29069436 Free article.
Validation of a Novel Multivariate Method of Defining HIV-Associated Cognitive Impairment.
Underwood J, De Francesco D, Cole JH, Caan MWA, van Zoest RA, Schmand BA, Sharp DJ, Sabin CA, Reiss P, Winston A; COmorBidity in Relation to AIDS (COBRA) Collaboration and the Pharmacokinetic and clinical Observations in PePle over fiftY (POPPY) Study Group. Underwood J, et al. Open Forum Infect Dis. 2019 May 3;6(6):ofz198. doi: 10.1093/ofid/ofz198. eCollection 2019 Jun. Open Forum Infect Dis. 2019. PMID: 31263729 Free PMC article.
Non-nucleoside reverse transcriptase inhibitor-based combination antiretroviral therapy is associated with lower cell-associated HIV RNA and DNA levels compared to protease inhibitor-based therapy.
Pasternak AO, Vroom J, Kootstra NA, Wit FW, de Bruin M, De Francesco D, Bakker M, Sabin CA, Winston A, Prins JM, Reiss P, Berkhout B; Co-morBidity in Relation to Aids (COBRA) Collaboration. Pasternak AO, et al. Elife. 2021 Aug 13;10:e68174. doi: 10.7554/eLife.68174. Elife. 2021. PMID: 34387543 Free PMC article.
Patterns of Co-occurring Comorbidities in People Living With HIV.
De Francesco D, Verboeket SO, Underwood J, Bagkeris E, Wit FW, Mallon PWG, Winston A, Reiss P, Sabin CA; Pharmacokinetic and Clinical Observations in PeoPle Over fiftY (POPPY) study and the AGEhIV Cohort Study. De Francesco D, et al. Open Forum Infect Dis. 2018 Oct 24;5(11):ofy272. doi: 10.1093/ofid/ofy272. eCollection 2018 Nov. Open Forum Infect Dis. 2018. PMID: 30465014 Free PMC article.
A single mRNA vaccine dose in COVID-19 patients boosts neutralizing antibodies against SARS-CoV-2 and variants of concern.
van Gils MJ, van Willigen HDG, Wynberg E, Han AX, van der Straten K, Burger JA, Poniman M, Oomen M, Tejjani K, Bouhuijs JH, Verveen A, Lebbink R, Dijkstra M, Appelman B, Lavell AHA, Caniels TG, Bontjer I, van Vught LA, Vlaar APJ, Sikkens JJ, Bomers MK, Russell CA, Kootstra NA, Sanders RW, Prins M, de Bree GJ, de Jong MD; RECoVERED Study Group. van Gils MJ, et al. Cell Rep Med. 2021 Dec 14;3(1):100486. doi: 10.1016/j.xcrm.2021.100486. eCollection 2022 Jan 18. Cell Rep Med. 2021. PMID: 35103254 Free PMC article.
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