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622 results

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Mepolizumab or Placebo for Eosinophilic Granulomatosis with Polyangiitis.
Wechsler ME, Akuthota P, Jayne D, Khoury P, Klion A, Langford CA, Merkel PA, Moosig F, Specks U, Cid MC, Luqmani R, Brown J, Mallett S, Philipson R, Yancey SW, Steinfeld J, Weller PF, Gleich GJ; EGPA Mepolizumab Study Team. Wechsler ME, et al. Among authors: gleich gj. N Engl J Med. 2017 May 18;376(20):1921-1932. doi: 10.1056/NEJMoa1702079. N Engl J Med. 2017. PMID: 28514601 Free PMC article. Clinical Trial.
Evaluation of clinical benefit from treatment with mepolizumab for patients with eosinophilic granulomatosis with polyangiitis.
Steinfeld J, Bradford ES, Brown J, Mallett S, Yancey SW, Akuthota P, Cid MC, Gleich GJ, Jayne D, Khoury P, Langford CA, Merkel PA, Moosig F, Specks U, Weller PF, Wechsler ME. Steinfeld J, et al. Among authors: gleich gj. J Allergy Clin Immunol. 2019 Jun;143(6):2170-2177. doi: 10.1016/j.jaci.2018.11.041. Epub 2018 Dec 19. J Allergy Clin Immunol. 2019. PMID: 30578883 Free PMC article. Clinical Trial.
Pulmonary Eosinophilic Granulomatosis with Polyangiitis Has IgG4 Plasma Cells and Immunoregulatory Features.
Dong ZM, Lin E, Wechsler ME, Weller PF, Klion AD, Bochner BS, Delker DA, Hazel MW, Fairfax K, Khoury P, Akuthota P, Merkel PA, Dyer AM, Langford C, Specks U, Gleich GJ, Chinchilli VM, Raby B, Yandell M, Clayton F. Dong ZM, et al. Among authors: gleich gj. Am J Pathol. 2020 Jul;190(7):1438-1448. doi: 10.1016/j.ajpath.2020.03.005. Epub 2020 Apr 3. Am J Pathol. 2020. PMID: 32251643 Free PMC article.
Treatment of patients with the hypereosinophilic syndrome with mepolizumab.
Rothenberg ME, Klion AD, Roufosse FE, Kahn JE, Weller PF, Simon HU, Schwartz LB, Rosenwasser LJ, Ring J, Griffin EF, Haig AE, Frewer PI, Parkin JM, Gleich GJ; Mepolizumab HES Study Group. Rothenberg ME, et al. Among authors: gleich gj. N Engl J Med. 2008 Mar 20;358(12):1215-28. doi: 10.1056/NEJMoa070812. Epub 2008 Mar 16. N Engl J Med. 2008. PMID: 18344568 Free article. Clinical Trial.
Update on immunogenicity in severe asthma: Experience with mepolizumab.
Ortega HG, Meyer E, Brusselle G, Asano K, Prazma CM, Albers FC, Mallett SA, Yancey SW, Gleich GJ. Ortega HG, et al. Among authors: gleich gj. J Allergy Clin Immunol Pract. 2019 Sep-Oct;7(7):2469-2475.e1. doi: 10.1016/j.jaip.2019.03.042. Epub 2019 Apr 5. J Allergy Clin Immunol Pract. 2019. PMID: 30954640 Free article. Clinical Trial. No abstract available.
Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial.
Roufosse F, Kahn JE, Rothenberg ME, Wardlaw AJ, Klion AD, Kirby SY, Gilson MJ, Bentley JH, Bradford ES, Yancey SW, Steinfeld J, Gleich GJ; HES Mepolizumab study group. Roufosse F, et al. Among authors: gleich gj. J Allergy Clin Immunol. 2020 Dec;146(6):1397-1405. doi: 10.1016/j.jaci.2020.08.037. Epub 2020 Sep 18. J Allergy Clin Immunol. 2020. PMID: 32956756 Free PMC article. Clinical Trial.
Urine eosinophil-derived neurotoxin: A potential marker of activity in select eosinophilic disorders.
Makiya MA, Khoury P, Kuang FL, Mata AD, Mahmood S, Bowman A, Espinoza D, Kovacs N, Brown T, Holland N, Wetzler L, Ware JM, Dyer AM, Akuthota P, Bochner BS, Chinchilli VM, Gleich GJ, Langford C, Merkel PA, Specks U, Weller PF, Wechsler ME, Prussin C, Fay MP, Klion AD. Makiya MA, et al. Among authors: gleich gj. Allergy. 2023 Jan;78(1):258-269. doi: 10.1111/all.15481. Epub 2022 Sep 1. Allergy. 2023. PMID: 35971862
The consequences of not having eosinophils.
Gleich GJ, Klion AD, Lee JJ, Weller PF. Gleich GJ, et al. Allergy. 2013 Jul;68(7):829-35. doi: 10.1111/all.12169. Epub 2013 Jun 6. Allergy. 2013. PMID: 23742015 Free PMC article. Review.
Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report.
Klion AD, Bochner BS, Gleich GJ, Nutman TB, Rothenberg ME, Simon HU, Wechsler ME, Weller PF; The Hypereosinophilic Syndromes Working Group. Klion AD, et al. Among authors: gleich gj. J Allergy Clin Immunol. 2006 Jun;117(6):1292-302. doi: 10.1016/j.jaci.2006.02.042. Epub 2006 May 3. J Allergy Clin Immunol. 2006. PMID: 16750989
622 results