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A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge.
Bolles M, Deming D, Long K, Agnihothram S, Whitmore A, Ferris M, Funkhouser W, Gralinski L, Totura A, Heise M, Baric RS. Bolles M, et al. Among authors: gralinski l. J Virol. 2011 Dec;85(23):12201-15. doi: 10.1128/JVI.06048-11. Epub 2011 Sep 21. J Virol. 2011. PMID: 21937658 Free PMC article.
Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling.
Peng X, Gralinski L, Armour CD, Ferris MT, Thomas MJ, Proll S, Bradel-Tretheway BG, Korth MJ, Castle JC, Biery MC, Bouzek HK, Haynor DR, Frieman MB, Heise M, Raymond CK, Baric RS, Katze MG. Peng X, et al. Among authors: gralinski l. mBio. 2010 Oct 26;1(5):e00206-10. doi: 10.1128/mBio.00206-10. mBio. 2010. PMID: 20978541 Free PMC article.
Successful vaccination strategies that protect aged mice from lethal challenge from influenza virus and heterologous severe acute respiratory syndrome coronavirus.
Sheahan T, Whitmore A, Long K, Ferris M, Rockx B, Funkhouser W, Donaldson E, Gralinski L, Collier M, Heise M, Davis N, Johnston R, Baric RS. Sheahan T, et al. Among authors: gralinski l. J Virol. 2011 Jan;85(1):217-30. doi: 10.1128/JVI.01805-10. Epub 2010 Oct 27. J Virol. 2011. PMID: 20980507 Free PMC article.
Genetic analysis of complex traits in the emerging Collaborative Cross.
Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, Gralinski LE, Bell TA, Didion JD, Hua K, Nehrenberg DL, Powell CL, Steigerwalt J, Xie Y, Kelada SN, Collins FS, Yang IV, Schwartz DA, Branstetter LA, Chesler EJ, Miller DR, Spence J, Liu EY, McMillan L, Sarkar A, Wang J, Wang W, Zhang Q, Broman KW, Korstanje R, Durrant C, Mott R, Iraqi FA, Pomp D, Threadgill D, de Villena FP, Churchill GA. Aylor DL, et al. Among authors: gralinski le. Genome Res. 2011 Aug;21(8):1213-22. doi: 10.1101/gr.111310.110. Epub 2011 Mar 15. Genome Res. 2011. PMID: 21406540 Free PMC article.
Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection.
Peng X, Gralinski L, Ferris MT, Frieman MB, Thomas MJ, Proll S, Korth MJ, Tisoncik JR, Heise M, Luo S, Schroth GP, Tumpey TM, Li C, Kawaoka Y, Baric RS, Katze MG. Peng X, et al. Among authors: gralinski l. mBio. 2011 Nov 15;2(6):e00198-11. doi: 10.1128/mBio.00198-11. Print 2011. mBio. 2011. PMID: 22086488 Free PMC article.
Expression quantitative trait Loci for extreme host response to influenza a in pre-collaborative cross mice.
Bottomly D, Ferris MT, Aicher LD, Rosenzweig E, Whitmore A, Aylor DL, Haagmans BL, Gralinski LE, Bradel-Tretheway BG, Bryan JT, Threadgill DW, de Villena FP, Baric RS, Katze MG, Heise M, McWeeney SK. Bottomly D, et al. Among authors: gralinski le. G3 (Bethesda). 2012 Feb;2(2):213-21. doi: 10.1534/g3.111.001800. Epub 2012 Feb 1. G3 (Bethesda). 2012. PMID: 22384400 Free PMC article.
Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells.
Sims AC, Tilton SC, Menachery VD, Gralinski LE, Schäfer A, Matzke MM, Webb-Robertson BJ, Chang J, Luna ML, Long CE, Shukla AK, Bankhead AR 3rd, Burkett SE, Zornetzer G, Tseng CT, Metz TO, Pickles R, McWeeney S, Smith RD, Katze MG, Waters KM, Baric RS. Sims AC, et al. Among authors: gralinski le. J Virol. 2013 Apr;87(7):3885-902. doi: 10.1128/JVI.02520-12. Epub 2013 Jan 30. J Virol. 2013. PMID: 23365422 Free PMC article.
86 results