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Highly accurate protein structure prediction for the human proteome.
Tunyasuvunakool K, Adler J, Wu Z, Green T, Zielinski M, Žídek A, Bridgland A, Cowie A, Meyer C, Laydon A, Velankar S, Kleywegt GJ, Bateman A, Evans R, Pritzel A, Figurnov M, Ronneberger O, Bates R, Kohl SAA, Potapenko A, Ballard AJ, Romera-Paredes B, Nikolov S, Jain R, Clancy E, Reiman D, Petersen S, Senior AW, Kavukcuoglu K, Birney E, Kohli P, Jumper J, Hassabis D. Tunyasuvunakool K, et al. Among authors: green t. Nature. 2021 Aug;596(7873):590-596. doi: 10.1038/s41586-021-03828-1. Epub 2021 Jul 22. Nature. 2021. PMID: 34293799 Free PMC article.
Human-level performance in 3D multiplayer games with population-based reinforcement learning.
Jaderberg M, Czarnecki WM, Dunning I, Marris L, Lever G, Castañeda AG, Beattie C, Rabinowitz NC, Morcos AS, Ruderman A, Sonnerat N, Green T, Deason L, Leibo JZ, Silver D, Hassabis D, Kavukcuoglu K, Graepel T. Jaderberg M, et al. Among authors: green t. Science. 2019 May 31;364(6443):859-865. doi: 10.1126/science.aau6249. Science. 2019. PMID: 31147514
Protein structure prediction using multiple deep neural networks in the 13th Critical Assessment of Protein Structure Prediction (CASP13).
Senior AW, Evans R, Jumper J, Kirkpatrick J, Sifre L, Green T, Qin C, Žídek A, Nelson AWR, Bridgland A, Penedones H, Petersen S, Simonyan K, Crossan S, Kohli P, Jones DT, Silver D, Kavukcuoglu K, Hassabis D. Senior AW, et al. Among authors: green t. Proteins. 2019 Dec;87(12):1141-1148. doi: 10.1002/prot.25834. Proteins. 2019. PMID: 31602685 Free PMC article.
Improved protein structure prediction using potentials from deep learning.
Senior AW, Evans R, Jumper J, Kirkpatrick J, Sifre L, Green T, Qin C, Žídek A, Nelson AWR, Bridgland A, Penedones H, Petersen S, Simonyan K, Crossan S, Kohli P, Jones DT, Silver D, Kavukcuoglu K, Hassabis D. Senior AW, et al. Among authors: green t. Nature. 2020 Jan;577(7792):706-710. doi: 10.1038/s41586-019-1923-7. Epub 2020 Jan 15. Nature. 2020. PMID: 31942072
Highly accurate protein structure prediction with AlphaFold.
Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, Tunyasuvunakool K, Bates R, Žídek A, Potapenko A, Bridgland A, Meyer C, Kohl SAA, Ballard AJ, Cowie A, Romera-Paredes B, Nikolov S, Jain R, Adler J, Back T, Petersen S, Reiman D, Clancy E, Zielinski M, Steinegger M, Pacholska M, Berghammer T, Bodenstein S, Silver D, Vinyals O, Senior AW, Kavukcuoglu K, Kohli P, Hassabis D. Jumper J, et al. Among authors: green t. Nature. 2021 Aug;596(7873):583-589. doi: 10.1038/s41586-021-03819-2. Epub 2021 Jul 15. Nature. 2021. PMID: 34265844 Free PMC article.
Applying and improving AlphaFold at CASP14.
Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, Tunyasuvunakool K, Bates R, Žídek A, Potapenko A, Bridgland A, Meyer C, Kohl SAA, Ballard AJ, Cowie A, Romera-Paredes B, Nikolov S, Jain R, Adler J, Back T, Petersen S, Reiman D, Clancy E, Zielinski M, Steinegger M, Pacholska M, Berghammer T, Silver D, Vinyals O, Senior AW, Kavukcuoglu K, Kohli P, Hassabis D. Jumper J, et al. Among authors: green t. Proteins. 2021 Dec;89(12):1711-1721. doi: 10.1002/prot.26257. Proteins. 2021. PMID: 34599769 Free PMC article.
AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models.
Varadi M, Anyango S, Deshpande M, Nair S, Natassia C, Yordanova G, Yuan D, Stroe O, Wood G, Laydon A, Žídek A, Green T, Tunyasuvunakool K, Petersen S, Jumper J, Clancy E, Green R, Vora A, Lutfi M, Figurnov M, Cowie A, Hobbs N, Kohli P, Kleywegt G, Birney E, Hassabis D, Velankar S. Varadi M, et al. Among authors: green r, green t. Nucleic Acids Res. 2022 Jan 7;50(D1):D439-D444. doi: 10.1093/nar/gkab1061. Nucleic Acids Res. 2022. PMID: 34791371 Free PMC article.
3D-Beacons: decreasing the gap between protein sequences and structures through a federated network of protein structure data resources.
Varadi M, Nair S, Sillitoe I, Tauriello G, Anyango S, Bienert S, Borges C, Deshpande M, Green T, Hassabis D, Hatos A, Hegedus T, Hekkelman ML, Joosten R, Jumper J, Laydon A, Molodenskiy D, Piovesan D, Salladini E, Salzberg SL, Sommer MJ, Steinegger M, Suhajda E, Svergun D, Tenorio-Ku L, Tosatto S, Tunyasuvunakool K, Waterhouse AM, Žídek A, Schwede T, Orengo C, Velankar S. Varadi M, et al. Among authors: green t. Gigascience. 2022 Nov 30;11:giac118. doi: 10.1093/gigascience/giac118. Gigascience. 2022. PMID: 36448847 Free PMC article.
AlphaFold Protein Structure Database in 2024: providing structure coverage for over 214 million protein sequences.
Varadi M, Bertoni D, Magana P, Paramval U, Pidruchna I, Radhakrishnan M, Tsenkov M, Nair S, Mirdita M, Yeo J, Kovalevskiy O, Tunyasuvunakool K, Laydon A, Žídek A, Tomlinson H, Hariharan D, Abrahamson J, Green T, Jumper J, Birney E, Steinegger M, Hassabis D, Velankar S. Varadi M, et al. Among authors: green t. Nucleic Acids Res. 2024 Jan 5;52(D1):D368-D375. doi: 10.1093/nar/gkad1011. Nucleic Acids Res. 2024. PMID: 37933859 Free PMC article.
Mitochondria inside acute myeloid leukemia cells hydrolyze ATP to resist chemotherapy.
Hagen JT, Montgomery MM, Aruleba RT, Chrest BR, Green TD, Kassai M, Zeczycki TN, Schmidt CA, Bhowmick D, Tan SF, Feith DJ, Chalfant CE, Loughran TP, Liles D, Minden MD, Schimmer AD, Cabot MC, Mclung JM, Fisher-Wellman KH. Hagen JT, et al. Among authors: green td. bioRxiv [Preprint]. 2024 Apr 15:2024.04.12.589110. doi: 10.1101/2024.04.12.589110. bioRxiv. 2024. PMID: 38659944 Free PMC article. Preprint.
2,064 results