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Fanconi anemia and homologous recombination gene variants are associated with functional DNA repair defects in vitro and poor outcome in patients with advanced head and neck squamous cell carcinoma.
Oncotarget. 2018 Apr 6;9(26):18198-18213. doi: 10.18632/oncotarget.24797. eCollection 2018 Apr 6.
Oncotarget. 2018.
PMID: 29719599
Free PMC article.
Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells.
Verhagen CV, de Haan R, Hageman F, Oostendorp TP, Carli AL, O'Connor MJ, Jonkers J, Verheij M, van den Brekel MW, Vens C.
Verhagen CV, et al. Among authors: hageman f.
Radiother Oncol. 2015 Sep;116(3):358-65. doi: 10.1016/j.radonc.2015.03.028. Epub 2015 May 13.
Radiother Oncol. 2015.
PMID: 25981132
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Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity.
Dohmen AJC, Qiao X, Duursma A, Wijdeven RH, Lieftink C, Hageman F, Morris B, Halonen P, Vens C, van den Brekel MWM, Ovaa H, Neefjes J, Zuur CL.
Dohmen AJC, et al. Among authors: hageman f.
Oncotarget. 2017 May 19;8(43):73925-73937. doi: 10.18632/oncotarget.18034. eCollection 2017 Sep 26.
Oncotarget. 2017.
PMID: 29088757
Free PMC article.
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