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An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.
Sheahan TP, Sims AC, Zhou S, Graham RL, Pruijssers AJ, Agostini ML, Leist SR, Schäfer A, Dinnon KH 3rd, Stevens LJ, Chappell JD, Lu X, Hughes TM, George AS, Hill CS, Montgomery SA, Brown AJ, Bluemling GR, Natchus MG, Saindane M, Kolykhalov AA, Painter G, Harcourt J, Tamin A, Thornburg NJ, Swanstrom R, Denison MR, Baric RS. Sheahan TP, et al. Among authors: harcourt j. Sci Transl Med. 2020 Apr 29;12(541):eabb5883. doi: 10.1126/scitranslmed.abb5883. Epub 2020 Apr 6. Sci Transl Med. 2020. PMID: 32253226 Free PMC article.
Monoclonal antibodies to SARS-associated coronavirus (SARS-CoV): identification of neutralizing and antibodies reactive to S, N, M and E viral proteins.
Tripp RA, Haynes LM, Moore D, Anderson B, Tamin A, Harcourt BH, Jones LP, Yilla M, Babcock GJ, Greenough T, Ambrosino DM, Alvarez R, Callaway J, Cavitt S, Kamrud K, Alterson H, Smith J, Harcourt JL, Miao C, Razdan R, Comer JA, Rollin PE, Ksiazek TG, Sanchez A, Rota PA, Bellini WJ, Anderson LJ. Tripp RA, et al. Among authors: harcourt jl, harcourt bh. J Virol Methods. 2005 Sep;128(1-2):21-8. doi: 10.1016/j.jviromet.2005.03.021. J Virol Methods. 2005. PMID: 15885812 Free PMC article.
Serologic Follow-up of Middle East Respiratory Syndrome Coronavirus Cases and Contacts-Abu Dhabi, United Arab Emirates.
Al Hosani FI, Kim L, Khudhair A, Pham H, Al Mulla M, Al Bandar Z, Pradeep K, Elkheir KA, Weber S, Khoury M, Donnelly G, Younis N, El Saleh F, Abdalla M, Imambaccus H, Haynes LM, Thornburg NJ, Harcourt JL, Miao C, Tamin A, Hall AJ, Russell ES, Harris AM, Kiebler C, Mir RA, Pringle K, Alami NN, Abedi GR, Gerber SI. Al Hosani FI, et al. Among authors: harcourt jl. Clin Infect Dis. 2019 Jan 18;68(3):409-418. doi: 10.1093/cid/ciy503. Clin Infect Dis. 2019. PMID: 29905769 Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States.
Harcourt J, Tamin A, Lu X, Kamili S, Sakthivel SK, Murray J, Queen K, Tao Y, Paden CR, Zhang J, Li Y, Uehara A, Wang H, Goldsmith C, Bullock HA, Wang L, Whitaker B, Lynch B, Gautam R, Schindewolf C, Lokugamage KG, Scharton D, Plante JA, Mirchandani D, Widen SG, Narayanan K, Makino S, Ksiazek TG, Plante KS, Weaver SC, Lindstrom S, Tong S, Menachery VD, Thornburg NJ. Harcourt J, et al. Emerg Infect Dis. 2020 Jun;26(6):1266-1273. doi: 10.3201/eid2606.200516. Epub 2020 Jun 17. Emerg Infect Dis. 2020. PMID: 32160149 Free PMC article.
Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1.
van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN, Tamin A, Harcourt JL, Thornburg NJ, Gerber SI, Lloyd-Smith JO, de Wit E, Munster VJ. van Doremalen N, et al. Among authors: harcourt jl. N Engl J Med. 2020 Apr 16;382(16):1564-1567. doi: 10.1056/NEJMc2004973. Epub 2020 Mar 17. N Engl J Med. 2020. PMID: 32182409 Free PMC article. No abstract available.
Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility.
Arons MM, Hatfield KM, Reddy SC, Kimball A, James A, Jacobs JR, Taylor J, Spicer K, Bardossy AC, Oakley LP, Tanwar S, Dyal JW, Harney J, Chisty Z, Bell JM, Methner M, Paul P, Carlson CM, McLaughlin HP, Thornburg N, Tong S, Tamin A, Tao Y, Uehara A, Harcourt J, Clark S, Brostrom-Smith C, Page LC, Kay M, Lewis J, Montgomery P, Stone ND, Clark TA, Honein MA, Duchin JS, Jernigan JA; Public Health–Seattle and King County and CDC COVID-19 Investigation Team. Arons MM, et al. Among authors: harcourt j. N Engl J Med. 2020 May 28;382(22):2081-2090. doi: 10.1056/NEJMoa2008457. Epub 2020 Apr 24. N Engl J Med. 2020. PMID: 32329971 Free PMC article.
Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient.
Harcourt J, Tamin A, Lu X, Kamili S, Sakthivel SK, Murray J, Queen K, Tao Y, Paden CR, Zhang J, Li Y, Uehara A, Wang H, Goldsmith C, Bullock HA, Wang L, Whitaker B, Lynch B, Gautam R, Schindewolf C, Lokugamage KG, Scharton D, Plante JA, Mirchandani D, Widen SG, Narayanan K, Makino S, Ksiazek TG, Plante KS, Weaver SC, Lindstrom S, Tong S, Menachery VD, Thornburg NJ. Harcourt J, et al. bioRxiv [Preprint]. 2020 Mar 7:2020.03.02.972935. doi: 10.1101/2020.03.02.972935. bioRxiv. 2020. PMID: 32511316 Free PMC article. Preprint.
225 results