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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1.
Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S. Duff K, et al. Among authors: harigaya y. Nature. 1996 Oct 24;383(6602):710-3. doi: 10.1038/383710a0. Nature. 1996. PMID: 8878479
Accumulation of beta-amyloid fibrils in pancreas of transgenic mice.
Kawarabayashi T, Shoji M, Sato M, Sasaki A, Ho L, Eckman CB, Prada CM, Younkin SG, Kobayashi T, Tada N, Matsubara E, Iizuka T, Harigaya Y, Kasai K, Hirai S. Kawarabayashi T, et al. Among authors: harigaya y. Neurobiol Aging. 1996 Mar-Apr;17(2):215-22. doi: 10.1016/0197-4580(95)02061-6. Neurobiol Aging. 1996. PMID: 8744402
Type-specific evolution of amyloid plaque and angiopathy in APPsw mice.
Harigaya Y, Tomidokoro Y, Ikeda M, Sasaki A, Kawarabayashi T, Matsubara E, Kanai M, Saido TC, Younkin SG, Shoji M. Harigaya Y, et al. Neurosci Lett. 2006 Feb 27;395(1):37-41. doi: 10.1016/j.neulet.2005.10.087. Epub 2005 Nov 18. Neurosci Lett. 2006. PMID: 16298484
Decreased level of brain acetylcholine and memory disturbance in APPsw mice.
Ikarashi Y, Harigaya Y, Tomidokoro Y, Kanai M, Ikeda M, Matsubara E, Kawarabayashi T, Kuribara H, Younkin SG, Maruyama Y, Shoji M. Ikarashi Y, et al. Among authors: harigaya y. Neurobiol Aging. 2004 Apr;25(4):483-90. doi: 10.1016/S0197-4580(03)00122-2. Neurobiol Aging. 2004. PMID: 15013569
Generation of amyloid beta protein from a presenilin-1 and betaAPP complex.
Shizuka-Ikeda M, Matsubara E, Ikeda M, Kanai M, Tomidokoro Y, Ikeda Y, Watanabe M, Kawarabayashi T, Harigaya Y, Okamoto K, Maruyama K, Castaño EM, St George-Hyslop P, Shoji M. Shizuka-Ikeda M, et al. Among authors: harigaya y. Biochem Biophys Res Commun. 2002 Mar 29;292(2):571-8. doi: 10.1006/bbrc.2002.6681. Biochem Biophys Res Commun. 2002. PMID: 11906199
Enhanced accumulation of phosphorylated alpha-synuclein in double transgenic mice expressing mutant beta-amyloid precursor protein and presenilin-1.
Kurata T, Kawarabayashi T, Murakami T, Miyazaki K, Morimoto N, Ohta Y, Takehisa Y, Nagai M, Ikeda M, Matsubara E, Westaway D, Hyslop PS, Harigaya Y, Kamiya T, Shoji M, Abe K. Kurata T, et al. Among authors: harigaya y. J Neurosci Res. 2007 Aug 1;85(10):2246-52. doi: 10.1002/jnr.21352. J Neurosci Res. 2007. PMID: 17526016
168 results