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Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes.
Terczyńska-Dyla E, Bibert S, Duong FH, Krol I, Jørgensen S, Collinet E, Kutalik Z, Aubert V, Cerny A, Kaiser L, Malinverni R, Mangia A, Moradpour D, Müllhaupt B, Negro F, Santoro R, Semela D, Semmo N; Swiss Hepatitis C Cohort Study Group; Heim MH, Bochud PY, Hartmann R. Terczyńska-Dyla E, et al. Among authors: hartmann r. Nat Commun. 2014 Dec 23;5:5699. doi: 10.1038/ncomms6699. Nat Commun. 2014. PMID: 25534433 Free article.
Corrigendum: reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes.
Terczyńska-Dyla E, Bibert S, Duong FHT, Krol I, Jørgensen S, Collinet E, Kutalik Z, Aubert V, Cerny A, Kaiser L, Malinverni R, Mangia A, Moradpour D, Müllhaupt B, Negro F, Santoro R, Semela D, Semmo N; Swiss Hepatitis C Cohort Study Group; Heim MH, Bochud PY, Hartmann R. Terczyńska-Dyla E, et al. Among authors: hartmann r. Nat Commun. 2015 Jun 29;6:7280. doi: 10.1038/ncomms8280. Nat Commun. 2015. PMID: 26118470 Free article. No abstract available.
Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses.
Holm CK, Rahbek SH, Gad HH, Bak RO, Jakobsen MR, Jiang Z, Hansen AL, Jensen SK, Sun C, Thomsen MK, Laustsen A, Nielsen CG, Severinsen K, Xiong Y, Burdette DL, Hornung V, Lebbink RJ, Duch M, Fitzgerald KA, Bahrami S, Mikkelsen JG, Hartmann R, Paludan SR. Holm CK, et al. Among authors: hartmann r. Nat Commun. 2016 Feb 19;7:10680. doi: 10.1038/ncomms10680. Nat Commun. 2016. PMID: 26893169 Free PMC article.
Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression.
Ferraris P, Chandra PK, Panigrahi R, Aboulnasr F, Chava S, Kurt R, Pawlotsky JM, Wilkens L, Osterlund P, Hartmann R, Balart LA, Wu T, Dash S. Ferraris P, et al. Among authors: hartmann r. Am J Pathol. 2016 Apr;186(4):938-51. doi: 10.1016/j.ajpath.2015.11.027. Epub 2016 Feb 16. Am J Pathol. 2016. PMID: 26896692 Free PMC article.
IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis.
Eslam M, McLeod D, Kelaeng KS, Mangia A, Berg T, Thabet K, Irving WL, Dore GJ, Sheridan D, Grønbæk H, Abate ML, Hartmann R, Bugianesi E, Spengler U, Rojas A, Booth DR, Weltman M, Mollison L, Cheng W, Riordan S, Mahajan H, Fischer J, Nattermann J, Douglas MW, Liddle C, Powell E, Romero-Gomez M, George J; International Liver Disease Genetics Consortium (ILDGC). Eslam M, et al. Among authors: hartmann r. Nat Genet. 2017 May;49(5):795-800. doi: 10.1038/ng.3836. Epub 2017 Apr 10. Nat Genet. 2017. PMID: 28394349 Free article.
Defective RNA sensing by RIG-I in severe influenza virus infection.
Jørgensen SE, Christiansen M, Ryø LB, Gad HH, Gjedsted J, Staeheli P, Mikkelsen JG, Storgaard M, Hartmann R, Mogensen TH. Jørgensen SE, et al. Among authors: hartmann r. Clin Exp Immunol. 2018 Jun;192(3):366-376. doi: 10.1111/cei.13120. Epub 2018 Mar 24. Clin Exp Immunol. 2018. PMID: 29453856 Free PMC article.
1,245 results