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LKB1 modulates lung cancer differentiation and metastasis.
Ji H, Ramsey MR, Hayes DN, Fan C, McNamara K, Kozlowski P, Torrice C, Wu MC, Shimamura T, Perera SA, Liang MC, Cai D, Naumov GN, Bao L, Contreras CM, Li D, Chen L, Krishnamurthy J, Koivunen J, Chirieac LR, Padera RF, Bronson RT, Lindeman NI, Christiani DC, Lin X, Shapiro GI, Jänne PA, Johnson BE, Meyerson M, Kwiatkowski DJ, Castrillon DH, Bardeesy N, Sharpless NE, Wong KK. Ji H, et al. Among authors: hayes dn. Nature. 2007 Aug 16;448(7155):807-10. doi: 10.1038/nature06030. Epub 2007 Aug 5. Nature. 2007. PMID: 17676035
LKB1 and lung cancer: more than the usual suspects.
Shah U, Sharpless NE, Hayes DN. Shah U, et al. Among authors: hayes dn. Cancer Res. 2008 May 15;68(10):3562-5. doi: 10.1158/0008-5472.CAN-07-6620. Cancer Res. 2008. PMID: 18483235 Review.
HIF2alpha cooperates with RAS to promote lung tumorigenesis in mice.
Kim WY, Perera S, Zhou B, Carretero J, Yeh JJ, Heathcote SA, Jackson AL, Nikolinakos P, Ospina B, Naumov G, Brandstetter KA, Weigman VJ, Zaghlul S, Hayes DN, Padera RF, Heymach JV, Kung AL, Sharpless NE, Kaelin WG Jr, Wong KK. Kim WY, et al. Among authors: hayes dn. J Clin Invest. 2009 Aug;119(8):2160-70. doi: 10.1172/jci38443. J Clin Invest. 2009. PMID: 19662677 Free PMC article.
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response.
Chen Z, Cheng K, Walton Z, Wang Y, Ebi H, Shimamura T, Liu Y, Tupper T, Ouyang J, Li J, Gao P, Woo MS, Xu C, Yanagita M, Altabef A, Wang S, Lee C, Nakada Y, Peña CG, Sun Y, Franchetti Y, Yao C, Saur A, Cameron MD, Nishino M, Hayes DN, Wilkerson MD, Roberts PJ, Lee CB, Bardeesy N, Butaney M, Chirieac LR, Costa DB, Jackman D, Sharpless NE, Castrillon DH, Demetri GD, Jänne PA, Pandolfi PP, Cantley LC, Kung AL, Engelman JA, Wong KK. Chen Z, et al. Among authors: hayes dn. Nature. 2012 Mar 18;483(7391):613-7. doi: 10.1038/nature10937. Nature. 2012. PMID: 22425996 Free PMC article.
Prediction of lung cancer histological types by RT-qPCR gene expression in FFPE specimens.
Wilkerson MD, Schallheim JM, Hayes DN, Roberts PJ, Bastien RR, Mullins M, Yin X, Miller CR, Thorne LB, Geiersbach KB, Muldrew KL, Funkhouser WK, Fan C, Hayward MC, Bayer S, Perou CM, Bernard PS. Wilkerson MD, et al. Among authors: hayes dn. J Mol Diagn. 2013 Jul;15(4):485-97. doi: 10.1016/j.jmoldx.2013.03.007. Epub 2013 May 20. J Mol Diagn. 2013. PMID: 23701907 Free PMC article.
Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer.
Liu Y, Marks K, Cowley GS, Carretero J, Liu Q, Nieland TJ, Xu C, Cohoon TJ, Gao P, Zhang Y, Chen Z, Altabef AB, Tchaicha JH, Wang X, Choe S, Driggers EM, Zhang J, Bailey ST, Sharpless NE, Hayes DN, Patel NM, Janne PA, Bardeesy N, Engelman JA, Manning BD, Shaw RJ, Asara JM, Scully R, Kimmelman A, Byers LA, Gibbons DL, Wistuba II, Heymach JV, Kwiatkowski DJ, Kim WY, Kung AL, Gray NS, Root DE, Cantley LC, Wong KK. Liu Y, et al. Among authors: hayes dn. Cancer Discov. 2013 Aug;3(8):870-9. doi: 10.1158/2159-8290.CD-13-0015. Epub 2013 May 28. Cancer Discov. 2013. PMID: 23715154 Free PMC article.
Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma.
Liao RG, Jung J, Tchaicha J, Wilkerson MD, Sivachenko A, Beauchamp EM, Liu Q, Pugh TJ, Pedamallu CS, Hayes DN, Gray NS, Getz G, Wong KK, Haddad RI, Meyerson M, Hammerman PS. Liao RG, et al. Among authors: hayes dn. Cancer Res. 2013 Aug 15;73(16):5195-205. doi: 10.1158/0008-5472.CAN-12-3950. Epub 2013 Jun 20. Cancer Res. 2013. PMID: 23786770 Free PMC article.
The Cancer Genome Atlas Pan-Cancer analysis project.
Cancer Genome Atlas Research Network; Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. Cancer Genome Atlas Research Network, et al. Nat Genet. 2013 Oct;45(10):1113-20. doi: 10.1038/ng.2764. Nat Genet. 2013. PMID: 24071849 Free PMC article.
298 results