Heemskerk N - Search Results

1

Rho-GTPase signaling in leukocyte extravasation: an endothelial point of view.

Heemskerk N, van Rijssel J, van Buul JD. Heemskerk N, et al. Cell Adh Migr. 2014;8(2):67-75. doi: 10.4161/cam.28244. Cell Adh Migr. 2014. PMID: 24621576 Free PMC article. Review.

2

The Ins and Outs of Small GTPase Rac1 in the Vasculature.

Marinković G, Heemskerk N, van Buul JD, de Waard V. Marinković G, et al. Among authors: heemskerk n. J Pharmacol Exp Ther. 2015 Aug;354(2):91-102. doi: 10.1124/jpet.115.223610. Epub 2015 Jun 2. J Pharmacol Exp Ther. 2015. PMID: 26036474 Review.

3

A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1.

Timmerman I, Heemskerk N, Kroon J, Schaefer A, van Rijssel J, Hoogenboezem M, van Unen J, Goedhart J, Gadella TW Jr, Yin T, Wu Y, Huveneers S, van Buul JD. Timmerman I, et al. Among authors: heemskerk n. J Cell Sci. 2015 Aug 15;128(16):3041-54. doi: 10.1242/jcs.168674. Epub 2015 Jun 26. J Cell Sci. 2015. PMID: 26116572

4

F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling.

Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, van Unen J, Pitter B, Huveneers S, Goedhart J, Wu Y, Montanez E, Woodfin A, van Buul JD. Heemskerk N, et al. Nat Commun. 2016 Jan 27;7:10493. doi: 10.1038/ncomms10493. Nat Commun. 2016. PMID: 26814335 Free PMC article.

5

Annexin A2 Limits Neutrophil Transendothelial Migration by Organizing the Spatial Distribution of ICAM-1.

Heemskerk N, Asimuddin M, Oort C, van Rijssel J, van Buul JD. Heemskerk N, et al. J Immunol. 2016 Mar 15;196(6):2767-78. doi: 10.4049/jimmunol.1501322. Epub 2016 Feb 10. J Immunol. 2016. PMID: 26864032 Free article.

6

Leukocyte transendothelial migration: A local affair.

Schimmel L, Heemskerk N, van Buul JD. Schimmel L, et al. Among authors: heemskerk n. Small GTPases. 2017 Jan 2;8(1):1-15. doi: 10.1080/21541248.2016.1197872. Epub 2016 Aug 15. Small GTPases. 2017. PMID: 27715453 Free PMC article. Review.

7

Flow-induced endothelial cell alignment requires the RhoGEF Trio as a scaffold protein to polarize active Rac1 distribution.

Kroon J, Heemskerk N, Kalsbeek MJT, de Waard V, van Rijssel J, van Buul JD. Kroon J, et al. Among authors: heemskerk n. Mol Biol Cell. 2017 Jul 1;28(13):1745-1753. doi: 10.1091/mbc.E16-06-0389. Epub 2017 May 17. Mol Biol Cell. 2017. PMID: 28515142 Free PMC article.

8

A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1.

Timmerman I, Heemskerk N, Kroon J, Schaefer A, van Rijssel J, Hoogenboezem M, van Unen J, Goedhart J, Gadella TW Jr, Yin T, Wu Y, Huveneers S, van Buul JD. Timmerman I, et al. Among authors: heemskerk n. J Cell Sci. 2015 Sep 15;128(18):3514. doi: 10.1242/jcs.179424. J Cell Sci. 2015. PMID: 26374854 Free PMC article. No abstract available.

9

A Window of Opportunity: Targeting Cancer Endothelium to Enhance Immunotherapy.

Duru G, van Egmond M, Heemskerk N. Duru G, et al. Among authors: heemskerk n. Front Immunol. 2020 Nov 11;11:584723. doi: 10.3389/fimmu.2020.584723. eCollection 2020. Front Immunol. 2020. PMID: 33262763 Free PMC article. Review.

10

EGFR-dependent tyrosine phosphorylation of integrin β4 is not required for downstream signaling events in cancer cell lines.

Te Molder L, Kreft M, Heemskerk N, Schuring J, de Pereda JM, Wilhelmsen K, Sonnenberg A. Te Molder L, et al. Among authors: heemskerk n. Sci Rep. 2021 Apr 21;11(1):8675. doi: 10.1038/s41598-021-88134-6. Sci Rep. 2021. PMID: 33883672 Free PMC article.

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