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An attenuating mutation in nsP1 of the Sindbis-group virus S.A.AR86 accelerates nonstructural protein processing and up-regulates viral 26S RNA synthesis.
Heise MT, White LJ, Simpson DA, Leonard C, Bernard KA, Meeker RB, Johnston RE. Heise MT, et al. J Virol. 2003 Jan;77(2):1149-56. doi: 10.1128/jvi.77.2.1149-1156.2003. J Virol. 2003. PMID: 12502831 Free PMC article.
Mutation of the nsP1 538 Thr to the consensus Ile found in nonneurovirulent Sindbis-group alphaviruses attenuates S.A.AR86 for adult mouse neurovirulence, while introduction of Thr at position 538 in a nonneurovirulent Sindbis virus background confers increased neurovirulence ( …
Mutation of the nsP1 538 Thr to the consensus Ile found in nonneurovirulent Sindbis-group alphaviruses attenuates S.A.AR86 for adult mouse n …
SARS coronavirus accessory ORFs encode luxury functions.
Frieman MB, Yount B, Sims AC, Deming DJ, Morrison TE, Sparks J, Denison M, Heise M, Baric RS. Frieman MB, et al. Among authors: heise m. Adv Exp Med Biol. 2006;581:149-52. doi: 10.1007/978-0-387-33012-9_26. Adv Exp Med Biol. 2006. PMID: 17037522 Free PMC article. No abstract available.
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c mice.
Roberts A, Deming D, Paddock CD, Cheng A, Yount B, Vogel L, Herman BD, Sheahan T, Heise M, Genrich GL, Zaki SR, Baric R, Subbarao K. Roberts A, et al. Among authors: heise m. PLoS Pathog. 2007 Jan;3(1):e5. doi: 10.1371/journal.ppat.0030005. PLoS Pathog. 2007. PMID: 17222058 Free PMC article. Clinical Trial.
SARS coronavirus and innate immunity.
Frieman M, Heise M, Baric R. Frieman M, et al. Among authors: heise m. Virus Res. 2008 Apr;133(1):101-12. doi: 10.1016/j.virusres.2007.03.015. Epub 2007 Apr 23. Virus Res. 2008. PMID: 17451827 Free PMC article. Review.
365 results