Hendriks BS - Search Results

1

Decreased internalisation of erbB1 mutants in lung cancer is linked with a mechanism conferring sensitivity to gefitinib.

Hendriks BS, Griffiths GJ, Benson R, Kenyon D, Lazzara M, Swinton J, Beck S, Hickinson M, Beusmans JM, Lauffenburger D, de Graaf D. Hendriks BS, et al. Syst Biol (Stevenage). 2006 Nov;153(6):457-66. doi: 10.1049/ip-syb:20050108. Syst Biol (Stevenage). 2006. PMID: 17186707

2

Computational modelling of ErbB family phosphorylation dynamics in response to transforming growth factor alpha and heregulin indicates spatial compartmentation of phosphatase activity.

Hendriks BS, Cook J, Burke JM, Beusmans JM, Lauffenburger DA, de Graaf D. Hendriks BS, et al. Syst Biol (Stevenage). 2006 Jan;153(1):22-33. doi: 10.1049/ip-syb:20050057. Syst Biol (Stevenage). 2006. PMID: 16983832

3

Parsing ERK activation reveals quantitatively equivalent contributions from epidermal growth factor receptor and HER2 in human mammary epithelial cells.

Hendriks BS, Orr G, Wells A, Wiley HS, Lauffenburger DA. Hendriks BS, et al. J Biol Chem. 2005 Feb 18;280(7):6157-69. doi: 10.1074/jbc.M410491200. Epub 2004 Nov 29. J Biol Chem. 2005. PMID: 15572377 Free article.

4

Applying computational modeling to drug discovery and development.

Kumar N, Hendriks BS, Janes KA, de Graaf D, Lauffenburger DA. Kumar N, et al. Among authors: hendriks bs. Drug Discov Today. 2006 Sep;11(17-18):806-11. doi: 10.1016/j.drudis.2006.07.010. Drug Discov Today. 2006. PMID: 16935748 Review.

5

HER2-mediated effects on EGFR endosomal sorting: analysis of biophysical mechanisms.

Hendriks BS, Wiley HS, Lauffenburger D. Hendriks BS, et al. Biophys J. 2003 Oct;85(4):2732-45. doi: 10.1016/S0006-3495(03)74696-7. Biophys J. 2003. PMID: 14507736 Free PMC article.

6

Quantitative analysis of HER2-mediated effects on HER2 and epidermal growth factor receptor endocytosis: distribution of homo- and heterodimers depends on relative HER2 levels.

Hendriks BS, Opresko LK, Wiley HS, Lauffenburger D. Hendriks BS, et al. J Biol Chem. 2003 Jun 27;278(26):23343-51. doi: 10.1074/jbc.M300477200. Epub 2003 Apr 9. J Biol Chem. 2003. PMID: 12686539 Free article.

7

Multiple effects of acetaminophen and p38 inhibitors: towards pathway toxicology.

Xu JJ, Hendriks BS, Zhao J, de Graaf D. Xu JJ, et al. Among authors: hendriks bs. FEBS Lett. 2008 Apr 9;582(8):1276-82. doi: 10.1016/j.febslet.2008.01.063. Epub 2008 Feb 20. FEBS Lett. 2008. PMID: 18282474 Free article. Review.

8

Coregulation of epidermal growth factor receptor/human epidermal growth factor receptor 2 (HER2) levels and locations: quantitative analysis of HER2 overexpression effects.

Hendriks BS, Opresko LK, Wiley HS, Lauffenburger D. Hendriks BS, et al. Cancer Res. 2003 Mar 1;63(5):1130-7. Cancer Res. 2003. PMID: 12615732

9

Elevated GM-CSF and IL-1beta levels compromise the ability of p38 MAPK inhibitors to modulate TNFalpha levels in the human monocytic/macrophage U937 cell line.

Espelin CW, Goldsipe A, Sorger PK, Lauffenburger DA, de Graaf D, Hendriks BS. Espelin CW, et al. Among authors: hendriks bs. Mol Biosyst. 2010 Oct;6(10):1956-72. doi: 10.1039/c002848g. Epub 2010 Jul 9. Mol Biosyst. 2010. PMID: 20617251

10

Synergistic drug-cytokine induction of hepatocellular death as an in vitro approach for the study of inflammation-associated idiosyncratic drug hepatotoxicity.

Cosgrove BD, King BM, Hasan MA, Alexopoulos LG, Farazi PA, Hendriks BS, Griffith LG, Sorger PK, Tidor B, Xu JJ, Lauffenburger DA. Cosgrove BD, et al. Among authors: hendriks bs. Toxicol Appl Pharmacol. 2009 Jun 15;237(3):317-30. doi: 10.1016/j.taap.2009.04.002. Epub 2009 Apr 9. Toxicol Appl Pharmacol. 2009. PMID: 19362101 Free PMC article.

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