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Page 1
Efficacy and Safety of Hydroxychloroquine vs Placebo for Pre-exposure SARS-CoV-2 Prophylaxis Among Health Care Workers: A Randomized Clinical Trial.
Abella BS, Jolkovsky EL, Biney BT, Uspal JE, Hyman MC, Frank I, Hensley SE, Gill S, Vogl DT, Maillard I, Babushok DV, Huang AC, Nasta SD, Walsh JC, Wiletyo EP, Gimotty PA, Milone MC, Amaravadi RK; Prevention and Treatment of COVID-19 With Hydroxychloroquine (PATCH) Investigators. Abella BS, et al. Among authors: hensley se. JAMA Intern Med. 2021 Feb 1;181(2):195-202. doi: 10.1001/jamainternmed.2020.6319. JAMA Intern Med. 2021. PMID: 33001138 Free PMC article. Clinical Trial.
Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions.
Mathew D, Giles JR, Baxter AE, Greenplate AR, Wu JE, Alanio C, Oldridge DA, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Hensley SE, Apostolidis S, Huang AC, Vella LA; UPenn COVID Processing Unit; Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. Among authors: hensley se. bioRxiv [Preprint]. 2020 May 23:2020.05.20.106401. doi: 10.1101/2020.05.20.106401. bioRxiv. 2020. PMID: 32511371 Free PMC article. Updated. Preprint.
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications.
Mathew D, Giles JR, Baxter AE, Oldridge DA, Greenplate AR, Wu JE, Alanio C, Kuri-Cervantes L, Pampena MB, D'Andrea K, Manne S, Chen Z, Huang YJ, Reilly JP, Weisman AR, Ittner CAG, Kuthuru O, Dougherty J, Nzingha K, Han N, Kim J, Pattekar A, Goodwin EC, Anderson EM, Weirick ME, Gouma S, Arevalo CP, Bolton MJ, Chen F, Lacey SF, Ramage H, Cherry S, Hensley SE, Apostolidis SA, Huang AC, Vella LA; UPenn COVID Processing Unit; Betts MR, Meyer NJ, Wherry EJ. Mathew D, et al. Among authors: hensley se. Science. 2020 Sep 4;369(6508):eabc8511. doi: 10.1126/science.abc8511. Epub 2020 Jul 15. Science. 2020. PMID: 32669297 Free PMC article.
Evidence of thrombotic microangiopathy in children with SARS-CoV-2 across the spectrum of clinical presentations.
Diorio C, McNerney KO, Lambert M, Paessler M, Anderson EM, Henrickson SE, Chase J, Liebling EJ, Burudpakdee C, Lee JH, Balamuth FB, Blatz AM, Chiotos K, Fitzgerald JC, Giglia TM, Gollomp K, Odom John AR, Jasen C, Leng T, Petrosa W, Vella LA, Witmer C, Sullivan KE, Laskin BL, Hensley SE, Bassiri H, Behrens EM, Teachey DT. Diorio C, et al. Among authors: hensley se. Blood Adv. 2020 Dec 8;4(23):6051-6063. doi: 10.1182/bloodadvances.2020003471. Blood Adv. 2020. PMID: 33290544 Free PMC article.
Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios.
Flannery DD, Gouma S, Dhudasia MB, Mukhopadhyay S, Pfeifer MR, Woodford EC, Triebwasser JE, Gerber JS, Morris JS, Weirick ME, McAllister CM, Bolton MJ, Arevalo CP, Anderson EM, Goodwin EC, Hensley SE, Puopolo KM. Flannery DD, et al. Among authors: hensley se. JAMA Pediatr. 2021 Jun 1;175(6):594-600. doi: 10.1001/jamapediatrics.2021.0038. JAMA Pediatr. 2021. PMID: 33512440 Free PMC article.
Sero-monitoring of health care workers reveals complex relationships between common coronavirus antibodies and SARS-CoV-2 severity.
Gouma S, Weirick ME, Bolton MJ, Arevalo CP, Goodwin EC, Anderson EM, McAllister CM, Christensen SR, Dunbar D, Fiore D, Brock A, Weaver J, Millar J, DerOhannessian S; UPenn COVID Processing Unit; Frank I, Rader DJ, Wherry EJ, Hensley SE. Gouma S, et al. Among authors: hensley se. medRxiv [Preprint]. 2021 Apr 19:2021.04.12.21255324. doi: 10.1101/2021.04.12.21255324. medRxiv. 2021. PMID: 33907765 Free PMC article. Updated. Preprint.
Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19.
Apostolidis SA, Sarkar A, Giannini HM, Goel RR, Mathew D, Suzuki A, Baxter AE, Greenplate AR, Alanio C, Abdel-Hakeem M, Oldridge DA, Giles J, Wu JE, Chen Z, Huang YJ, Pattekar A, Manne S, Kuthuru O, Dougherty J, Weiderhold B, Weisman AR, Ittner CAG, Gouma S, Dunbar D, Frank I, Huang AC, Vella LA; UPenn COVID Processing Unit; Reilly JP, Hensley SE, Rauova L, Zhao L, Meyer NJ, Poncz M, Abrams CS, Wherry EJ. Apostolidis SA, et al. Among authors: hensley se. bioRxiv [Preprint]. 2021 May 3:2021.05.01.442279. doi: 10.1101/2021.05.01.442279. bioRxiv. 2021. PMID: 33972943 Free PMC article. Updated. Preprint.
Vaccination reshapes the virus-specific T cell repertoire in unexposed adults.
Pan YG, Aiamkitsumrit B, Bartolo L, Wang Y, Lavery C, Marc A, Holec PV, Rappazzo CG, Eilola T, Gimotty PA, Hensley SE, Antia R, Zarnitsyna VI, Birnbaum ME, Su LF. Pan YG, et al. Among authors: hensley se. Immunity. 2021 Jun 8;54(6):1245-1256.e5. doi: 10.1016/j.immuni.2021.04.023. Epub 2021 May 18. Immunity. 2021. PMID: 34004140 Free PMC article.
CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer.
Bange EM, Han NA, Wileyto P, Kim JY, Gouma S, Robinson J, Greenplate AR, Hwee MA, Porterfield F, Owoyemi O, Naik K, Zheng C, Galantino M, Weisman AR, Ittner CAG, Kugler EM, Baxter AE, Oniyide O, Agyekum RS, Dunn TG, Jones TK, Giannini HM, Weirick ME, McAllister CM, Babady NE, Kumar A, Widman AJ, DeWolf S, Boutemine SR, Roberts C, Budzik KR, Tollett S, Wright C, Perloff T, Sun L, Mathew D, Giles JR, Oldridge DA, Wu JE, Alanio C, Adamski S, Garfall AL, Vella LA, Kerr SJ, Cohen JV, Oyer RA, Massa R, Maillard IP, Maxwell KN, Reilly JP, Maslak PG, Vonderheide RH, Wolchok JD, Hensley SE, Wherry EJ, Meyer NJ, DeMichele AM, Vardhana SA, Mamtani R, Huang AC. Bange EM, et al. Among authors: hensley se. Nat Med. 2021 Jul;27(7):1280-1289. doi: 10.1038/s41591-021-01386-7. Epub 2021 May 20. Nat Med. 2021. PMID: 34017137 Free PMC article.
SARS-CoV-2 Seropositivity and Seroconversion in Patients Undergoing Active Cancer-Directed Therapy.
Sun L, Surya S, Goodman NG, Le AN, Kelly G, Owoyemi O, Desai H, Zheng C, DeLuca S, Good ML, Hussain J, Jeffries SD, Kry YR, Kugler EM, Mansour M, Ndicu J, Osei-Akoto A, Prior T, Pundock SL, Varughese LA, Weaver J, Doucette A, Dudek S, Verma SS, Gouma S, Weirick ME, McAllister CM, Bange E, Gabriel P, Ritchie M, Rader DJ, Vonderheide RH, Schuchter LM, Verma A, Maillard I, Mamtani R, Hensley SE, Gross R, Wileyto EP, Huang AC, Maxwell KN, DeMichele A. Sun L, et al. Among authors: hensley se. JCO Oncol Pract. 2021 Dec;17(12):e1879-e1886. doi: 10.1200/OP.21.00113. Epub 2021 Jun 16. JCO Oncol Pract. 2021. PMID: 34133219 Free PMC article.
141 results