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Decreased internalisation of erbB1 mutants in lung cancer is linked with a mechanism conferring sensitivity to gefitinib.
Syst Biol (Stevenage). 2006 Nov;153(6):457-66. doi: 10.1049/ip-syb:20050108.
Syst Biol (Stevenage). 2006.
PMID: 17186707
Inhibitors of epidermal growth factor receptor tyrosine kinase: optimisation of potency and in vivo pharmacokinetics.
Ballard P, Bradbury RH, Harris CS, Hennequin LF, Hickinson M, Kettle JG, Kendrew J, Klinowska T, Ogilvie DJ, Pearson SE, Williams EJ, Wilson I.
Ballard P, et al. Among authors: hickinson m.
Bioorg Med Chem Lett. 2006 Sep 15;16(18):4908-12. doi: 10.1016/j.bmcl.2006.06.054. Epub 2006 Jun 27.
Bioorg Med Chem Lett. 2006.
PMID: 16806916
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Inhibitors of epidermal growth factor receptor tyrosine kinase: Novel C-5 substituted anilinoquinazolines designed to target the ribose pocket.
Ballard P, Bradbury RH, Harris CS, Hennequin LF, Hickinson M, Johnson PD, Kettle JG, Klinowska T, Leach AG, Morgentin R, Pass M, Ogilvie DJ, Olivier A, Warin N, Williams EJ.
Ballard P, et al. Among authors: hickinson m.
Bioorg Med Chem Lett. 2006 Mar 15;16(6):1633-7. doi: 10.1016/j.bmcl.2005.12.028. Epub 2005 Dec 27.
Bioorg Med Chem Lett. 2006.
PMID: 16380259
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Novel 3-alkoxy-1H-pyrazolo[3,4-d]pyrimidines as EGFR and erbB2 receptor tyrosine kinase inhibitors.
Ducray R, Ballard P, Barlaam BC, Hickinson MD, Kettle JG, Ogilvie DJ, Trigwell CB.
Ducray R, et al. Among authors: hickinson md.
Bioorg Med Chem Lett. 2008 Feb 1;18(3):959-62. doi: 10.1016/j.bmcl.2007.12.035. Epub 2007 Dec 23.
Bioorg Med Chem Lett. 2008.
PMID: 18182285
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