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Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel.
Ference BA, Ginsberg HN, Graham I, Ray KK, Packard CJ, Bruckert E, Hegele RA, Krauss RM, Raal FJ, Schunkert H, Watts GF, Borén J, Fazio S, Horton JD, Masana L, Nicholls SJ, Nordestgaard BG, van de Sluis B, Taskinen MR, Tokgözoglu L, Landmesser U, Laufs U, Wiklund O, Stock JK, Chapman MJ, Catapano AL. Ference BA, et al. Among authors: horton jd. Eur Heart J. 2017 Aug 21;38(32):2459-2472. doi: 10.1093/eurheartj/ehx144. Eur Heart J. 2017. PMID: 28444290 Free PMC article. Review.
Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel.
Borén J, Chapman MJ, Krauss RM, Packard CJ, Bentzon JF, Binder CJ, Daemen MJ, Demer LL, Hegele RA, Nicholls SJ, Nordestgaard BG, Watts GF, Bruckert E, Fazio S, Ference BA, Graham I, Horton JD, Landmesser U, Laufs U, Masana L, Pasterkamp G, Raal FJ, Ray KK, Schunkert H, Taskinen MR, van de Sluis B, Wiklund O, Tokgozoglu L, Catapano AL, Ginsberg HN. Borén J, et al. Among authors: horton jd. Eur Heart J. 2020 Jun 21;41(24):2313-2330. doi: 10.1093/eurheartj/ehz962. Eur Heart J. 2020. PMID: 32052833 Free PMC article. No abstract available.
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9.
Rashid S, Curtis DE, Garuti R, Anderson NN, Bashmakov Y, Ho YK, Hammer RE, Moon YA, Horton JD. Rashid S, et al. Among authors: horton jd. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5374-9. doi: 10.1073/pnas.0501652102. Epub 2005 Apr 1. Proc Natl Acad Sci U S A. 2005. PMID: 15805190 Free PMC article.
Genetic and metabolic determinants of plasma PCSK9 levels.
Lakoski SG, Lagace TA, Cohen JC, Horton JD, Hobbs HH. Lakoski SG, et al. Among authors: horton jd. J Clin Endocrinol Metab. 2009 Jul;94(7):2537-43. doi: 10.1210/jc.2009-0141. Epub 2009 Apr 7. J Clin Endocrinol Metab. 2009. PMID: 19351729 Free PMC article.
CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL.
Bartuzi P, Billadeau DD, Favier R, Rong S, Dekker D, Fedoseienko A, Fieten H, Wijers M, Levels JH, Huijkman N, Kloosterhuis N, van der Molen H, Brufau G, Groen AK, Elliott AM, Kuivenhoven JA, Plecko B, Grangl G, McGaughran J, Horton JD, Burstein E, Hofker MH, van de Sluis B. Bartuzi P, et al. Among authors: horton jd. Nat Commun. 2016 Mar 11;7:10961. doi: 10.1038/ncomms10961. Nat Commun. 2016. PMID: 26965651 Free PMC article.
209 results