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An anti-HIV-1 V3 loop antibody fully protects cross-clade and elicits T-cell immunity in macaques mucosally challenged with an R5 clade C SHIV.
Watkins JD, Siddappa NB, Lakhashe SK, Humbert M, Sholukh A, Hemashettar G, Wong YL, Yoon JK, Wang W, Novembre FJ, Villinger F, Ibegbu C, Patel K, Corti D, Agatic G, Vanzetta F, Bianchi S, Heeney JL, Sallusto F, Lanzavecchia A, Ruprecht RM. Watkins JD, et al. Among authors: humbert m. PLoS One. 2011 Mar 31;6(3):e18207. doi: 10.1371/journal.pone.0018207. PLoS One. 2011. PMID: 21483815 Free PMC article.
Isolation of monoclonal antibodies with predetermined conformational epitope specificity.
Sholukh AM, Mukhtar MM, Humbert M, Essono SS, Watkins JD, Vyas HK, Shanmuganathan V, Hemashettar G, Kahn M, Hu SL, Montefiori DC, Polonis VR, Schur PH, Ruprecht RM. Sholukh AM, et al. Among authors: humbert m. PLoS One. 2012;7(6):e38943. doi: 10.1371/journal.pone.0038943. Epub 2012 Jun 21. PLoS One. 2012. PMID: 22737224 Free PMC article.
Adaptation of an R5 Simian-Human Immunodeficiency Virus Encoding an HIV Clade A Envelope with or without Ablation of Adaptive Host Immunity: Differential Selection of Viral Mutants.
Zhou M, Humbert M, Mukhtar MM, Scinto HB, Vyas HK, Lakhashe SK, Byrareddy SN, Maurer G, Thorat S, Owuor J, Lai Z, Chen Y, Griffiths A, Chenine AL, Gumber S, Villinger F, Montefiori D, Ruprecht RM. Zhou M, et al. Among authors: humbert m. J Virol. 2019 Apr 17;93(9):e02267-18. doi: 10.1128/JVI.02267-18. Print 2019 May 1. J Virol. 2019. PMID: 30760566 Free PMC article.
Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens.
Zhang MY, Vu BK, Choudhary A, Lu H, Humbert M, Ong H, Alam M, Ruprecht RM, Quinnan G, Jiang S, Montefiori DC, Mascola JR, Broder CC, Haynes BF, Dimitrov DS. Zhang MY, et al. Among authors: humbert m. J Virol. 2008 Jul;82(14):6869-79. doi: 10.1128/JVI.00033-08. Epub 2008 May 14. J Virol. 2008. PMID: 18480433 Free PMC article.
1,366 results