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Conservative Oxygen Therapy during Mechanical Ventilation in the ICU.
ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group; Mackle D, Bellomo R, Bailey M, Beasley R, Deane A, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R, Young P; ICU-ROX Investigators the Australian and New Zealand Intensive Care Society Clinical Trials Group. ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group, et al. N Engl J Med. 2020 Mar 12;382(11):989-998. doi: 10.1056/NEJMoa1903297. Epub 2019 Oct 14. N Engl J Med. 2020. PMID: 31613432 Clinical Trial.
CONCLUSIONS: In adults undergoing mechanical ventilation in the ICU, the use of conservative oxygen therapy, as compared with usual oxygen therapy, did not significantly affect the number of ventilator-free days. (Funded by the Health Research Council of New Zealand; IC …
CONCLUSIONS: In adults undergoing mechanical ventilation in the ICU, the use of conservative oxygen therapy, as compared with usual oxygen t …
Intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX): results of the pilot phase.
Young PJ, Mackle DM, Bailey MJ, Beasley RW, Bennett VL, Deane AM, Eastwood GM, Finfer S, Freebairn RC, Litton E, Linke NJ, McArthur CJ, McGuinness SP, Panwar R, Bellomo R; The ICU-ROX pilot investigators; The Australian and New Zealand Intensive Care Society Clinical Trials Group. Young PJ, et al. Crit Care Resusc. 2017 Dec;19(4):344-354. Crit Care Resusc. 2017. PMID: 29202261 Clinical Trial.
OBJECTIVE: The objective of the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX) pilot phase, which included the first 100 patients of an overall sample of 1000, was to examine feasibility. ...CONCLUSIONS: Our findings confir …
OBJECTIVE: The objective of the intensive care unit randomised trial comparing two approaches to oxygen therapy (ICU-ROX) pilo …
Conservative oxygen therapy for mechanically ventilated adults with suspected hypoxic ischaemic encephalopathy.
Young P, Mackle D, Bellomo R, Bailey M, Beasley R, Deane A, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R; ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Young P, et al. Intensive Care Med. 2020 Dec;46(12):2411-2422. doi: 10.1007/s00134-020-06196-y. Epub 2020 Aug 18. Intensive Care Med. 2020. PMID: 32809136 Free PMC article. Clinical Trial.
Conservative or liberal oxygen therapy for mechanically ventilated adults with acute brain pathologies: A post-hoc subgroup analysis.
Young PJ, Mackle D, Hodgson C, Bellomo R, Bailey M, Beasley R, Deane AM, Eastwood G, Finfer S, Freebairn R, King V, Linke N, Litton E, McArthur C, McGuinness S, Panwar R; ICU-ROX Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Young PJ, et al. J Crit Care. 2022 Oct;71:154079. doi: 10.1016/j.jcrc.2022.154079. Epub 2022 Jun 2. J Crit Care. 2022. PMID: 35660843
MATERIALS AND METHODS: Post-hoc analysis of data from 217 patients with non-HIE acute brain pathologies included in the ICU Randomized Trial Comparing Two Approaches to OXygen therapy (ICU-ROX). RESULTS: Patients allocated to conservative oxygen spent less time with …
MATERIALS AND METHODS: Post-hoc analysis of data from 217 patients with non-HIE acute brain pathologies included in the ICU Randomized Trial …