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Does the impact of intensive lifestyle intervention on cognitive function vary depending baseline level of frailty? An ancillary study to the Action for Health in Diabetes (Look AHEAD) Trial.
J Diabetes Complications. 2021 May;35(5):107909. doi: 10.1016/j.jdiacomp.2021.107909. Epub 2021 Mar 16.
J Diabetes Complications. 2021.
PMID: 33745805
Free PMC article.
METHODS: Standardized cognitive assessments were collected following 8 years of either ILI or a control condition of diabetes support and education (DSE) in 3708 individuals, ages 45-76 years at enrollment, with type 2 diabetes and overweight or obesity. ...T …
METHODS: Standardized cognitive assessments were collected following 8 years of either ILI or a control condition of diabetes support …
Impact of Multidomain Lifestyle Intervention on Frailty Through the Lens of Deficit Accumulation in Adults with Type 2 Diabetes Mellitus.
Simpson FR, Pajewski NM, Nicklas B, Kritchevsky S, Bertoni A, Ingram F, Ojeranti D, Espeland MA; Indices for Accelerated Aging in Obesity and Diabetes Ancillary Study of the Action for Health in Diabetes (Look AHEAD) Trial.
Simpson FR, et al.
J Gerontol A Biol Sci Med Sci. 2020 Sep 25;75(10):1921-1927. doi: 10.1093/gerona/glz197.
J Gerontol A Biol Sci Med Sci. 2020.
PMID: 31559418
Free PMC article.
Clinical Trial.
BACKGROUND: Type 2 diabetes and obesity increase the accumulation of health deficits and may accelerate biological aging. ...We used two complementary frailty indices (FIs) based on deficit accumulation, one modeled on work in the Systolic Blood …
BACKGROUND: Type 2 diabetes and obesity increase the accumulation of health deficits and may accelerate biological a …
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