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Association studies of novel obesity-related gene variants with quantitative metabolic phenotypes in a population-based sample of 6,039 Danish individuals.
Burgdorf KS, Gjesing AP, Grarup N, Justesen JM, Sandholt CH, Witte DR, Jørgensen T, Madsbad S, Hansen T, Pedersen O. Burgdorf KS, et al. Among authors: jorgensen t. Diabetologia. 2012 Jan;55(1):105-13. doi: 10.1007/s00125-011-2320-4. Epub 2011 Sep 28. Diabetologia. 2012. PMID: 21953277 Clinical Trial.
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.
Sparsø T, Andersen G, Nielsen T, Burgdorf KS, Gjesing AP, Nielsen AL, Albrechtsen A, Rasmussen SS, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O. Sparsø T, et al. Among authors: jorgensen t. Diabetologia. 2008 Jan;51(1):70-5. doi: 10.1007/s00125-007-0865-z. Epub 2007 Nov 16. Diabetologia. 2008. PMID: 18008060
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.
Sparsø T, Andersen G, Albrechtsen A, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Wasson J, Permutt MA, Glaser B, Madsbad S, Pedersen O, Hansen T. Sparsø T, et al. Among authors: jorgensen t. Diabetologia. 2008 Sep;51(9):1646-52. doi: 10.1007/s00125-008-1064-2. Epub 2008 Jun 21. Diabetologia. 2008. PMID: 18568334
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.
Sparsø T, Grarup N, Andreasen C, Albrechtsen A, Holmkvist J, Andersen G, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O. Sparsø T, et al. Among authors: jorgensen t. Diabetologia. 2009 Jul;52(7):1308-14. doi: 10.1007/s00125-009-1362-3. Epub 2009 Apr 29. Diabetologia. 2009. PMID: 19404609
Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people.
Boesgaard TW, Grarup N, Jørgensen T, Borch-Johnsen K; Meta-Analysis of Glucose and Insulin-Related Trait Consortium (MAGIC); Hansen T, Pedersen O. Boesgaard TW, et al. Among authors: jorgensen t. Diabetologia. 2010 Aug;53(8):1647-55. doi: 10.1007/s00125-010-1753-5. Epub 2010 Apr 26. Diabetologia. 2010. PMID: 20419449 Free article.
1,807 results